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Georg Matziolis

Researcher at University of Jena

Publications -  114
Citations -  1408

Georg Matziolis is an academic researcher from University of Jena. The author has contributed to research in topics: Arthroplasty & Mesenchymal stem cell. The author has an hindex of 16, co-authored 114 publications receiving 1106 citations. Previous affiliations of Georg Matziolis include Charité.

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Current failure mechanisms after knee arthroplasty have changed: polyethylene wear is less common in revision surgery.

TL;DR: Aseptic loosening, instability, malalignment, and periprosthetic infection continue to be the primary failure mechanisms leading to revision surgery, with a substantial reduction in implant-associated revisions such as those due to polyethylene wear.
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Dose–Response Relationship of Mesenchymal Stem Cell Transplantation and Functional Regeneration After Severe Skeletal Muscle Injury in Rats

TL;DR: The logarithmic dose-response relationship demonstrates the association between the number of transplanted cells and the resulting muscle forces, as well as the amount of MSCs required for promoting muscular regeneration.
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Toward biomimetic materials in bone regeneration: functional behavior of mesenchymal stem cells on a broad spectrum of extracellular matrix components.

TL;DR: This study examined in parallel, for the first time, the effects on the functional behavior of MSCs of 13 ECM components from bone, cartilage and hematoma compared to a control protein and draws conclusions for rational biomaterial design.
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Time course of skeletal muscle regeneration after severe trauma.

TL;DR: The trauma model allows investigation of muscle regeneration after a standardized injury to muscle fibers and shows a clear time course concerning microstructure and T1 and T2 signal intensity.
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Locally applied osteogenic predifferentiated progenitor cells are more effective than undifferentiated mesenchymal stem cells in the treatment of delayed bone healing.

TL;DR: There were no significant differences in outcome measures between the MSC group and the Sham group, and the percutaneous injection of OPCs could become a minimally invasive treatment option for delayed or nonunions.