G
George P. Yang
Researcher at University of Alabama at Birmingham
Publications - 78
Citations - 4781
George P. Yang is an academic researcher from University of Alabama at Birmingham. The author has contributed to research in topics: Keloid & Wound healing. The author has an hindex of 26, co-authored 76 publications receiving 4410 citations. Previous affiliations of George P. Yang include VA Palo Alto Healthcare System & Veterans Health Administration.
Papers
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Journal ArticleDOI
Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271
Alexander D. Boiko,Olga V. Razorenova,Matt van de Rijn,Susan M. Swetter,Susan M. Swetter,Denise L. Johnson,Daphne P. Ly,Paris D. Butler,George P. Yang,George P. Yang,Benzion Joshua,Michael J. Kaplan,Michael T. Longaker,Irving L. Weissman +13 more
TL;DR: In mice, tumours derived from transplanted human CD271+ melanoma cells were capable of metastatsis in vivo, which helps to explain why T-cell therapies directed at these antigens usually result in only temporary tumour shrinkage.
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Gene Expression Programs in Response to Hypoxia: Cell Type Specificity and Prognostic Significance in Human Cancers
Jen-Tsan Chi,Jen-Tsan Chi,Zhen Wang,Dimitry S.A. Nuyten,Edwin H. Rodriguez,Marci E. Schaner,Ali Salim,Yun Wang,Gunnar B. Kristensen,Åslaug Helland,Anne Lise Børresen-Dale,Amato J. Giaccia,Michael T. Longaker,Trevor Hastie,George P. Yang,Marc J. van de Vijver,Patrick O. Brown +16 more
TL;DR: A gene-expression signature of the hypoxia response, derived from studies of cultured mammary and renal tubular epithelial cells, showed coordinated variation in several human cancers, and was a strong predictor of clinical outcomes in breast and ovarian cancers.
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Phase I study of stereotactic radiosurgery in patients with locally advanced pancreatic cancer.
Albert C. Koong,Q.T. Le,Anthony Ho,Bryan Fong,George A. Fisher,Cheryl D. Cho,James M. Ford,Joseph C. Poen,Iris C. Gibbs,Vivek K. Mehta,Stephen T. Kee,Ward Trueblood,George P. Yang,J. Augusto Bastidas +13 more
TL;DR: It is feasible to deliver stereotactic radiosurgery to patients with locally advanced pancreatic cancer and the recommended dose to achieve local control without significant acute gastrointestinal toxicity is 25 Gy.
Journal ArticleDOI
Phase II study to assess the efficacy of conventionally fractionated radiotherapy followed by a stereotactic radiosurgery boost in patients with locally advanced pancreatic cancer
Albert C. Koong,Erin Christofferson,Quynh-Thu Le,Karyn A. Goodman,Anthony Ho,Timothy Kuo,James M. Ford,George A. Fisher,Ralph S. Greco,Jeffrey A. Norton,George P. Yang +10 more
TL;DR: Conurrent IMRT and 5-FU followed by SRS in patients with locally advanced pancreatic cancer results in excellent local control, but does not improve overall survival and is associated with more toxicity than SRS, alone.
Journal ArticleDOI
Combining SSH and cDNA microarrays for rapid identification of differentially expressed genes
TL;DR: It is concluded that SSH and microarray technology can be successfully applied to identify differentially expressed genes without the need to obtain previously cloned cDNAs.