G
Gilbert Kirsch
Researcher at University of Lorraine
Publications - 241
Citations - 3227
Gilbert Kirsch is an academic researcher from University of Lorraine. The author has contributed to research in topics: Aryl & Thiophene. The author has an hindex of 32, co-authored 234 publications receiving 2871 citations. Previous affiliations of Gilbert Kirsch include Centre national de la recherche scientifique & Metz.
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Thienylpyrrole azo dyes : Synthesis, solvatochromic and electrochemical properties
TL;DR: In this paper, the synthesis and evaluation of new donor-acceptor-substituted thienylpyrrole azo dyes are described, which exhibit dramatic changes in both their electronic and redox properties in comparison with traditional push-pull derivatives.
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Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells.
Sergio Valente,Yiwei Liu,Michael Schnekenburger,Clemens Zwergel,Sandro Cosconati,Christina Gros,Maria Tardugno,Donatella Labella,Cristina Florean,Steven Minden,Hideharu Hashimoto,Xing Zhang,Gilbert Kirsch,Ettore Novellino,Paola B. Arimondo,Evelina Miele,Elisabetta Ferretti,Alberto Gulino,Marc Diederich,Xiaodong Cheng,Antonello Mai +20 more
TL;DR: Through a process of hit-to-lead optimization, compound 5 was found as a potent non-nucleoside DNMTi that is also selective toward other AdoMet-dependent protein methyltransferases and was less toxic in peripheral blood mononuclear cells than two other compounds tested.
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Synthesis of donor–acceptor substituted oligothiophenes by Stille coupling
TL;DR: In this paper, a synthesis of donor-acceptor-substituted oligothiophenes by Stille coupling is described, and the 5′-estanyl derivatives, readily prepared from 5-alkoxy- and 5-amino-2,2′-bithiophenses 7 were coupled with the appropriate aryl or heteroaryl bromides to give the title compounds.
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Synthesis of Five- and Six-Membered Heterocycles Through Palladium- Catalyzed Reactions
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Natural and Synthetic Coumarins with Effects on Inflammation.
TL;DR: This review, which will present the different aspects of coumarins and derivatives, from natural origins or synthetically prepared, and their action on inflammation, will take into account everything published since 2004.