Giulia Scioscia

TL;DR: Differences in sputum miRNA expression profile were observed between patients with ACOS and asthma or COPD, which underline the potential role of miRNA as a biomarker that is able to discriminate patients withACOS, asthma, and COPD.

TL;DR: Dyspnoea perception during CO2 rebreathing is enhanced in FE and blunted in IE, and these differences may contribute to the differential rate of reported exacerbations inFE and IE.

TL;DR: The efficacy of mepolizumab in terms of reduction of inflammation and increase of control that the patients observed in the authors' patients might suggest that targeting the IL-5 in severe eosinophilic asthma with bronchiectasis may be a good therapeutic strategy.

TL;DR: In this article, the authors evaluated the therapeutic effects of benralizumab in patients with severe uncontrolled, corticosteroid refractory eosinophilic asthma, and evaluated the efficacy of the anti-IL-5 receptor humanized monoclonal antibody with regard to positive or negative skin prick test.

TL;DR: Tocilizumab may be effective for the treatment of severe COVID-19 disease, even in patients with elevated liver function tests, and further studies are needed to evaluate the impact of tocilIZumab use on liver function Tests in patientsWith pre-existing chronic liver disease.