Giuliana Scarpati

TL;DR: In this paper, the role of Magnesium in chronic non-communicable diseases and infectious diseases and their association with disease outcomes is discussed. But, despite many methodological limitations, existing data seem to corroborate an association between deranged magnesium homeostasis and COVID-19, and call for further and better studies to explore the prophylactic or therapeutic potential of magnesium supplementation.

TL;DR: In this article, the authors synthesize the available information and evidence on both repositioned and experimental drugs for the treatment of COVID-19, focusing on the need to exercise caution on the use of unproven medical therapies.

TL;DR: In this article, the authors describe the main investigations leading to the discovery of RDV and its subsequent development as an antiviral agent, focusing on the main clinical trials investigating its efficacy in terms of symptom resolution and mortality reduction.

TL;DR: The basic principles of the interaction between inflammatory and coagulation systems are revised, from the perspective that simultaneous modulation of both coagulations and inflammation, rather than specific therapies aimed at one of these systems could be more successful in stroke therapy.

TL;DR: Whether it is better to measure ionized serum Mg or total serum MG when assessing magnesium status, whether iMg predicts clinical outcome, and what are the difficulties in measuring serum iMG levels in intensive care patients and perioperative medicine are analyzed.