G
Goli B Naderi
Researcher at Novartis
Publications - 2
Citations - 862
Goli B Naderi is an academic researcher from Novartis. The author has contributed to research in topics: Dipeptidyl peptidase & Dipeptidyl peptidase-4. The author has an hindex of 2, co-authored 2 publications receiving 830 citations.
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1-[[(3-hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties.
Edwin Bernard Villhauer,John A Brinkman,Goli B Naderi,Bryan Burkey,Beth E. Dunning,Kapa Prasad,Bonnie L Mangold,Mary E Russell,Thomas Edward Hughes +8 more
TL;DR: The results suggest that 12j is a potent, stable, selective DPP-IV inhibitor possessing excellent oral bioavailability and potent antihyperglycemic activity with potential for once-a-day administration.
Journal ArticleDOI
1-[2-[(5-Cyanopyridin-2-yl)amino]ethylamino]acetyl-2-(S)-pyrrolidinecarbonitrile: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties.
Edwin Bernard Villhauer,John A Brinkman,Goli B Naderi,Beth E. Dunning,Bonnie L Mangold,Manisha Mone,Mary E Russell,Stephen Craig Weldon,Thomas Edward Hughes +8 more
TL;DR: One compound, NVP-DPP728, is profiled as a potent, selective, and short-acting DPP-IV inhibitor that has excellent oral bioavailability and potent antihyperglycemic activity.