G
Graham M. Kyne
Researcher at Zoetis
Publications - 18
Citations - 443
Graham M. Kyne is an academic researcher from Zoetis. The author has contributed to research in topics: Enantioselective synthesis & Carboxylate. The author has an hindex of 6, co-authored 17 publications receiving 428 citations. Previous affiliations of Graham M. Kyne include University of Southampton & Florida State University.
Papers
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Journal ArticleDOI
Synthetic receptors for carboxylic acids and carboxylates
Journal ArticleDOI
Enantioselective amino acid recognition using acyclic thiourea receptors
TL;DR: A series of acyclic thiourea derivatives, designed to create a cleft with four hydrogen bond donors suitable for carboxylate recognition, have been prepared, and their ability to bind to N-protected amino acid CARB salts has been investigated.
Journal ArticleDOI
A highly enantioselective receptor for N-protected glutamate and anomalous solvent-dependent binding properties
TL;DR: The receptor was designed to produce a chiral pocket for dicarboxylates by forming up to eight hydrogen-bonding interactions with the carboxylate oxygen atoms and intramolecular hydrogen bonding with the pyridine unit to help preorganize the receptor.
Patent
Isoxazoline derivatives as antiparasitic agents
TL;DR: In this article, isoxazoline substituted derivatives of Formula (1) stereoisomer thereof, geometric isomers thereof, veterinarily acceptable salts 5 thereof, compositions thereof, and their use as a parasiticide in animals.
Patent
Pyrrolo [ 2, 3 - d] pyrimidine urea compounds as jak inhibitors
TL;DR: The present paper as discussed by the authors provides pyrrolo{2,3-d}pyrimidine compounds, their use as Janus Kinase (JAK) inhibitors, pharmaceutical compositions containing this compounds, and methods for the preparation of these compounds.