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Gui-Rong Li
Researcher at Li Ka Shing Faculty of Medicine, University of Hong Kong
Publications - 94
Citations - 6416
Gui-Rong Li is an academic researcher from Li Ka Shing Faculty of Medicine, University of Hong Kong. The author has contributed to research in topics: Repolarization & Patch clamp. The author has an hindex of 39, co-authored 92 publications receiving 6165 citations. Previous affiliations of Gui-Rong Li include University of Hong Kong & Yale University.
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Ionic Remodeling Underlying Action Potential Changes in a Canine Model of Atrial Fibrillation
TL;DR: It is concluded that sustained atrial tachycardia reduces Ito and ICa, that the reduced ICa decreases APD and APD adaptation to rate, and that these cellular changes likely account for the alterations in atrial refractoriness associated with enhanced ability to maintain AF in the model.
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Evidence for Two Components of Delayed Rectifier K+ Current in Human Ventricular Myocytes
TL;DR: It is concluded that a functionally significant IK, with components corresponding to IKr and IKs, is present in human ventricular cells, whereas IKur appears to be absent.
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Antisense Oligodeoxynucleotides Directed Against Kv1.5 mRNA Specifically Inhibit Ultrarapid Delayed Rectifier K+ Current in Cultured Adult Human Atrial Myocytes
TL;DR: These studies provide the first direct evidence with an antisense approach for the equivalence between a macroscopic cardiac K+ current and a cloned K+ channel subunit and offer insights into the molecular electrophysiology of the human heart.
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Transmural action potential and ionic current remodeling in ventricles of failing canine hearts.
TL;DR: It is indicated that HF remodels electrophysiology in all layers of the left ventricle, and the downregulation of I(K1), I(to1), and I(ks) increases APD and favors occurrence of EADs.
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Transmural heterogeneity of action potentials and Ito1 in myocytes isolated from the human right ventricle.
TL;DR: The results indicate that M cells in humans, as in canines, show the greatest APD and that a gradient of I to1 density is present in the transmural ventricular wall.