Showing papers by "Gülin Öz published in 1999"

Metallothionein structure update

Abstract: Metallothioneins (MTs) are low molecular weight (2–7 kDa), cysteine-rich proteins which bind with high affinity to metal ions, such as Zn(II), Cd(II), Cu(I) and Ag(I), in unusual metal-thiolate clusters [1-3] MT biosynthesis is induced by a wide range of factors, including metal ions, oxidative stress, glucocorticoid hormones and cytokines, leading to their implication in many diverse cellular processes However, the primary function of MTs under normal physiological conditions is in the transport and storage of the essential metals: zinc and copper