G
Guo Chaoshe
Publications - 40
Citations - 52
Guo Chaoshe is an academic researcher. The author has contributed to research in topics: Genetically modified organism & Chimeric gene. The author has an hindex of 3, co-authored 40 publications receiving 52 citations.
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Patent
Genetically modified non-human animal with human or chimeric pd-l1
TL;DR: In this article, a genetically modified expressing human or chemeric (e.g., humanized) programmed deathligand 1 (PD-L1, PDL1 or B7-H1) and methods of use thereof are discussed.
Patent
Genetically modified non-human animal with human or chimeric ox40
TL;DR: In this article, genetically modified non-human animals that express a human or chimeric OX40, and methods of use thereof are provided, provided that the animals are genetically modified.
Patent
Genetically modified non-human animal with human or chimeric lag-3
TL;DR: In this paper, the anti-LAG-3 antibody was administered to a non-human animal that expressed a human or chimeric Lymphocyte Activation Gene 3 (LAG) expression.
Patent
Humanized cytokine animal model, preparation method and application
Shen Yuelei,Zhang Meiling,Yao Jiawei,Guo Chaoshe,Guo Yanan,Bai Yang,Huang Rui,Zhao Lei,Shang Chengzhang +8 more
TL;DR: In this paper, a construction method of the humanized inhuman animal containing IL-6R and/or IL 6R gene modification, and an application of the construction method to the field of biopharmaceutical is presented.
Patent
Preparation method of humanized CD73 gene animal model and application thereof
Shen Yuelei,Guo Yanan,Bai Yang,Huang Rui,Shang Chengzhang,Zhang Meiling,Yao Jiawei,Guo Chaoshe +7 more
TL;DR: In this paper, the authors described a preparation method of a humanized CD73 gene animal model and an application thereof, particularly related to a genetically modified rodent, but particularly relating to genetically modified mouse, and particularly relates to a construction method of the animal model for expressing humanized or humanised CD73 protein.