The invention provides a detection method for the fingerprint of storesin medicinal components in a heart-protecting musk pill and application thereof. The method includes: preparation of a test solution and a control solution, determination and acquisition of a liquid chromatogram of the test solution and a liquid chromatogram of the control solution, and comparison of the liquid chromatogram of the test solution with the liquid chromatogram of the control solution, thus obtaining the fingerprint of 5 storesin medicinal components in the test solution. The invention also further provides application of the fingerprint detection method in content determination of 5 index components in the storesin medicinal components of the heart-protecting musk pill. Through fingerprint and content analysis of the 5 index components in the storesin medicinal components, multi-component quantitative control of the storesin quality can be realized, the quality control level of storesin in the heart-protecting musk pill can be enhanced, and certain reference is also provided for quality control of storesin in other compound preparations.

Detection method for fingerprint of storesin medicinal components in heart-protecting musk pill and application thereof

The invention provides an application of a toad cake to preparation of a medicament for suppressing biosynthesis of oleic acid (OA) and linoleic acid (LA). In a toad cake administration group animal, the metabolic level of AA (Arachidonic Acid) rises, and the metabolic levels of LA and OA fall, which indicate that the toxic and side effects of the toad cake can be used for suppressing the biosynthesis of LA and OA. Metabolic disorder of AA greatly influences normal functions of a heart, can cause reduction in the contraction force of the heart and reduction in cardiac output and can even induce or aggravate myocardial infarct and angina pectoris. By suppressing the biosynthesis of LA and OA through the toad cake, the content of the toad cake in a medicament can be adjusted reasonably, and heart diseases can be better treated or prevented.

Guoan Luo

Papers

Application of toad cake to preparation of medicament for suppressing biosynthesis of oleic acid (OA) and linoleic acid (LA)