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Showing papers by "Gustavo Velasquez-Melendez published in 2009"


Journal ArticleDOI
TL;DR: Multivariate analysis found risk factors associated to insulin resistance for non-diabetic adults with low income and educational level: overweight, obesity, elevated waist-to-hip ratio, C-reactive protein and skin color.
Abstract: This study explores the relations of anthropometric, body composition assessments, biochemical and hemodynamic parameters with insulin resistance in two rural communities. Sample was composed by adults aged 18 or older, both sexes. Participants were excluded if pregnant and diabetic. Data collection included demographic lifestyle, hemodynamic, anthropometric and biochemical variables. From the 567 subjects, 50.4% were men and 49.6%, women. Most of the sample was non-white (75.7%), lived with partner (69.3%) and had low educational level. Overweight and obesity prevalences were 17.4% and 5.5%, respectively. Multivariate analysis found risk factors associated to insulin resistance for non-diabetic adults with low income and educational level: overweight, obesity, elevated waist-to-hip ratio, C-reactive protein and skin color.

21 citations


Journal ArticleDOI
TL;DR: The results of this study do not support any association between work hours and incidence of hypertension in university graduates of a Spanish dynamic prospective cohort of university graduates.
Abstract: ObjectiveThe aim of this study was to assess the association between work hours and incidence of hypertension in 8779 participants of a Spanish dynamic prospective cohort of university graduates.MethodsThe baseline questionnaire included information about the weekly number of hours the participants

19 citations


Journal ArticleDOI
TL;DR: The findings corroborate the hypothesis that at least 3 pathophysiological domains act in the clustering of cardiovascular risk factors related to metabolic syndrome in this population of Brazil.
Abstract: The objective of this study was to verify the clustering of anthropometric and metabolic variables related to metabolic syndrome, by sex. Data were collected from 579 subjects aged 18-94 years living in two rural areas of Brazil. Factor analysis was performed using principal components analysis with varimax orthogonal rotation. The study reduced a complex set of cardiovascular risk factor into 3 independent factors, each reflecting a different aspect of metabolic syndrome. In both sexes, factor 1 related to obesity and dyslipidemia, factor 2 to obesity and blood pressure, and factor 3 to obesity and insulin resistance. The total variance explained for men and women was, respectively, 66.61% and 68.98%. The findings corroborate the hypothesis that at least 3 pathophysiological domains act in the clustering of cardiovascular risk factors related to metabolic syndrome in this population.

13 citations


Journal Article
TL;DR: The independent association of traditional risk factors for cardiovascular disease (age, sex, BMI, fasting insulin and HDL-c) with PCR evidences a close relationship between adipose tissue, cardiovascular diseases and inflammation.
Abstract: Association between adiposity measures, demographic and biochemical variables with C-reactive protein serum levels in rural population. Acute-phase proteins as C-reactive protein (CRP) have been associated with cardiovascular diseases. Recent studies have shown the relation between body fat and elevated serum levels of CRP. This study verifies relation between adiposity measures, demographic and biochemical variables with CRP serum levels in a rural population. The study was conducted among individuals aged 18 or more, both sexes and at least two years of residency in the place of study. Pregnant women, diabetic and CRP over 10 mg/l individuals were excluded. Data collection included anthropometric, demographic, lifestyle and biochemical variables. Data was processed in STATA 9.0. From the 536 subjects, 50.37% were men. Age varied from 18 to 94, age mean was 43.34. Overweight and obesity prevalence were significantly higher among women than men. Bivariate analysis found significant correlations between lnCRP and the following variables: BMI, waist circumference, WHR, age, education, systolic and diastolic blood pressure, total cholesterol, LDL-c, HDL-c, triglycerides, fasting insulin and HOMA-IR. After adjusting for confounding variables in multiple linear regression analysis only BMI, age, sex, fasting insulin and HDL-c remained significantly associated with lnCRP. The independent association of traditional risk factors for cardiovascular disease (age, sex, BMI, fasting insulin and HDL-c) with PCR evidences a close relationship between adipose tissue, cardiovascular diseases and inflammation.

7 citations


Journal Article
TL;DR: Multivariate analysis found risk factors associated to insulin resistance for non-diabetic adults with low income and educational level: overweight, obesity, elevated waist-to-hip ratio, C-reactive protein and skin color.
Abstract: This study explores the relations of anthropometric, body composition assessments, biochemical and hemodynamic parameters with insulin resistance in two rural communities. Sample was composed by adults aged 18 or older, both sexes. Participants were excluded if pregnant and diabetic. Data collection included demographic lifestyle, hemodynamic, anthropometric and biochemical variables. From the 567 subjects, 50,4% were men and 49,6%, women. Most of the sample was non-white (75,7%), lived with partner (69,3%) and had low educational level. Overweight and obesity prevalences were 17,4% and 5,5%, respectively. Multivariate analysis found risk factors associated to insulin resistance for non-diabetic adults with low income and educational level: overweight, obesity, elevated waist-to-hip ratio, C-reactive protein and skin color.

1 citations