H
H Amstutz
Researcher at Swiss Red Cross
Publications - 1
Citations - 1034
H Amstutz is an academic researcher from Swiss Red Cross. The author has contributed to research in topics: Chinese hamster ovary cell & Antibody-dependent cell-mediated cytotoxicity. The author has an hindex of 1, co-authored 1 publications receiving 1013 citations.
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Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity
TL;DR: The glycosylation pattern of chCE7 was engineered in Chinese hamster ovary cells with tetracycline–regulated expression of GnTIII to optimize the ADCC activity, and this activity correlated with the level of constant region–associated, bisected complex oligosaccharides determined by matrix–assisted laser desorption/ionization time–of–flight mass spectrometry.