The main development in macromolecular complexation in aqueous media due to hydrogen bonding over the last decade has been a better understanding of the process of complex formation. Meanwhile an ever growing interest has occurred in introducing hydrogen bonding into the polymers which originally lack donor or acceptor groups. For such polymer solutions it has been demonstrated that the transition from separated coils to complex aggregates takes place when the content of introduced interaction sites reaches a certain level. For the blends with controllable hydrogen bonding in the solid state, the relevant experiments have shown that immiscibility-miscibility-complexation transitions occur upon progressive increase in the density of hydrogen bonding.

Interpolymer Complexation and Miscibility Enhancement by Hydrogen Bonding

Unusual pH-Dependent Polarity Changes in PAMAM Dendrimers: Evidence for pH-Responsive Conformational Changes

The contribution of anionic polymer structural features to mucoadhesion

The effect of pH on the complex formation between poly(acrylic acid) (PAA) and poly(ethylene oxide) (PEO) has been studied in aqueous solutions by turbidimetric and fluorescent methods It was shown that the formation of insoluble interpolymer complexes is observed below a certain critical pH of complexation (pHcrit1) The formation of hydrophilic interpolymer associates is possible above pHcrit1 and below a certain pHcrit2 The effects of polymer concentrations in solution and PEO molecular weight as well as inorganic salt addition on these critical pH values were studied The polymeric films based on blends of PAA and PEO were prepared by casting from aqueous solutions with different pHs These films were characterized by light transmittance measurements and differential scanning calorimetry The existence of the pH value above which the polymers form an immiscible blend was demonstrated The transitions between the interpolymer complex, miscible blend, and immiscible blend caused by pH changes are disc

PH effects in the complex formation and blending of poly(acrylic acid) with poly(ethylene oxide).

Complexing blends of polyacrylic acid-polyethylene glycol and poly(ethylene-co-acrylic acid)-polyethylene glycol as shape stabilized phase change materials

Fluorometric study of the equilibrium and kinetics of poly(acrylic acid) association with polyoxyethylene or poly(vinyl pyrrolidone)

Objective: To investigate the clinical features of JAK2V617F gene mutation and non-mutation in patients with Budd-Chiari syndrome (BCS). Methods: 17 and 127 BCS cases with JAK2V617F gene mutation (mutation group) and non-gene mutation (non-mutation group) who were continuously treated with interventional therapy between January 2016 to December 2020 in the Affiliated Hospital of Xuzhou Medical University were selected as the research object for a comparative study. The hospitalization and follow-up data of the two groups were analyzed retrospectively, and the deadline for follow-up was June 2021. Quantitative data group differences were analyzed using the independent sample t-test and Wilcoxon rank sum test. Qualitative data group differences were analyzed with χ2 test or Fisher's exact test. Mann-Whitney U test was used to analyze the differences between groups in rank data. Kaplan-Meier method was used to calculate the patient survival and recurrence rate. Results: Age [(35.41±17.10) years vs. (50.09±14.16) years, t=3.915, P<0.001], time of onset (median duration: 3 months vs. 12 months), and the cumulative survival rate (65.5% vs 95.1%; χ2=5.21, P=0.022) were lower in mutation than non-mutation group. Aaspartate aminotransferase, alanine aminotransferase, prothrombin time, Child-Pugh score, Rotterdam score, Model for End-stage Liver Disease score, hepatic vein thrombosis incidence, and the cumulative recurrence rate after intervention were higher in mutation than non-mutation group. The above all indexes had statistically significant differences (P<0.05) between the groups. Conclusion: Younger age, acute onset, severe liver injury, high incidence of hepatic vein thrombosis, and poor prognosis are the features of patients with BCS with JAK2V617F gene mutation than non-mutation.

H.-L. Chen

Papers

Fluorometric study of the equilibrium and kinetics of poly(acrylic acid) association with polyoxyethylene or poly(vinyl pyrrolidone)

[Comparison of clinical features of JAK2V617F gene mutation and non-mutation in patients with Budd-Chiari syndrome].

[Leishmaniasis in a childhood acute lymphoblastic leukemia in complete remission: a case report].