H. Peng

TL;DR: WA was shown to be a strong inhibitor of the inflammatory response in islets, protecting against cytokine-induced cell damage while improving survival of transplanted islets and suggesting that WA could be incorporated as an adjunctive treatment to improve islet transplant outcome.

TL;DR: Comparing human fresh islets to cultured islets with in vitro and in vivo assays suggests that human islet transplantation without culture could avoid the deterioration of islets during culture and improve the outcome of islet transplants.

TL;DR: In vitro and in vivo assays suggest that the quality of islets was similar among the three groups and efficacy of purification and quality of isolated islets is similar when the osmolality of purifying solutions is between 400 and 500 mOsm/kg and density adjustment is applied.

TL;DR: Induction therapy with several growth factors and transduction proteins might provide a potential new strategy for induction of transplantable insulin-producing cells.

TL;DR: Three new enzymes (MTF, NB1, and CI) may enable us to obtain higher islet yields than with HI, and are evaluated herein.