H
H. Saito
Researcher at Iwate Medical University
Publications - 21
Citations - 214
H. Saito is an academic researcher from Iwate Medical University. The author has contributed to research in topics: Acetylcholine & Monoamine neurotransmitter. The author has an hindex of 9, co-authored 21 publications receiving 210 citations.
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Journal ArticleDOI
Rapid and simultaneous assay of monoamine neurotransmitters and their metabolites in discrete brain areas of mice by HPLC with Coulometric detection
TL;DR: The present procedure was applied to measure the target substrates in several discrete brain areas in mice to enable simultaneous assay of the three monoamine neurotransmitters, norepinephrine, dopamine, and serotonin, and four respective metabolites in brain tissue.
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A rapid assay for neurotransmitter amino acids, aspartate, glutamate, glycine, taurine and γ-aminobutyric acid in the brain by high-performance liquid chromatography with electrochemical detection
TL;DR: A very rapid and simple chromatographic method using high-performance liquid chromatography with electrochemical detection in combination with o-phthalaldehyde derivatization to measure amino acid neurotransmitter levels in several discrete brain regions of mice treated with and without electroconvulsive shock is described.
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MKC-231, a choline uptake enhancer, ameliorates working memory deficits and decreased hippocampal acetylcholine induced by ethylcholine aziridinium ion in mice
TL;DR: Results indicate that MKC-231 improved the AF64A-induced working memory deficit and hippocampal ACh depletion, probably by recovering reduced high-affinity choline uptake and ACh release.
Journal ArticleDOI
Regulatory Effect of Danggui-Shaoyao-San on Central Cholinergic Nervous System Dysfunction in Mice
Tadanobu Itoh,S. Michijiri,Shigeo Murai,H. Saito,K Nakamura,Osamu Itsukaichi,Hideyo Fujiwara,N Ookubo +7 more
TL;DR: The results indicate that TSS ameliorates dysfunction of the central cholinergic nervous system and scopolamine-induced decrease in ACh levels in mouse brain, but has no influence on A Ch levels in naive mice, suggesting that T SS may be a useful therapeutic agent in Alzheimer's disease and senile dementia.
Journal ArticleDOI
Basal levels of noradrenaline, dopamine, 5-hydroxytryptamine, and acetylcholine in the submandibular, parotid, and sublingual glands of mice and rats
TL;DR: Results show that in mouse and rat salivary glands, species differences in neurotransmitter distribution are relatively small, whereas there are considerable differences in distribution between the salivARY glands.