Biomedical devices with stable, hydrophilic and antimicrobial coatings are provided. The coatings are formed using a coupling agent to bond a carboxyl containing hydrophilic coating to the surface by ester or amide linkages.

Biomedical devices with hydrophilic coatings

Methods for preventing and/or eliminating fogging of endoscope lenses during an endoscopic procedure which include the steps of introducing an endoscope into a body cavity and contacting the endoscope lens with a biocompatible and biodegradable composition containing a polyalkylene oxide while the lens is positioned within the body. Alternatively, the endoscope may be coated with a biocompatible polyHEMA coating which is activated by a biocompatible solution, such as water or saline, which may be introduced during use through a fluid conduit on the endoscope. Devices for preventing and/or eliminating fogging of endoscope lenses during endoscopic procedures and conveying antifogging solutions to the distal end of the endoscope are also provided, and may include a distensible applicator.

Compositions, methods and apparatus for inhibiting fogging of endoscope lenses

The invention is related to a hydrated silicone hydrogel contact lens having a layered structural configuration: a lower water content silicone hydrogel core (or bulk material) completely covered with a layer of a higher water content hydrogel totally or substantially free of silicone. A hydrated silicone hydrogel contact lens of the invention possesses high oxygen permeability for maintaining the corneal health and a soft, water-rich, lubricious surface for wearing comfort.

Silicone hydrogel lenses with water-rich surfaces

An inorganic coating film having improved water repellency is provided. The improved surface is provided by treating an inorganic coating film with a material that is reached or adsorbed on the surface of the inorganic coat to increase water repellency. The inorganic coating to be treated may be a silicon dioxide film. The materials used to treat the film include: (1) halogenated silane compounds; (2) silane compounds having a structure including at least one bond selected from Si--H, Si--OH, Si--OR, Si--SH and Si--SR, wherein R is an organic group; (3) silane compounds having a structure including at least one of ##STR1## wherein R1, R2 and R3 are hydrogen or an organic group and (4) reactive organic compounds having a fluorine substituting group, hydrogen fluoride or a metal fluoride.

Synthetic resin ophthalmic lens having an inorganic coating

A method is disclosed for producing a micro structure on the surface of an article. The method comprises the steps of depositing a discontinuous coating of a material exhibiting a low rate of sputter etching on a substrate exhibiting a higher rate of sputter etching and differentially sputter etching the composite surface to produce a topography of pyramid-like micropedestals random in height and separation. The articles produced by this method are characterized by both the microstructured surface and by the detectable presence of the material exhibiting the lower rate of sputter etching. The microstructured surface results in the articles having uniform antireflecting properties over a large range of angles of incident light and over an extremely broad range of wavelengths, in which the antireflecting characteristic is obtained without an attendant increase in diffuse scattering. Also, the microstructured surface results in the articles being characterized by a high degree of adherence, such that the treated surface may be considered to be "primed", thereby enabling the application of highly adherent coatings or layers thereon.

Method of producing a microstructured surface and the article produced thereby

A method for coating silicon oxide SiO film and silicon dioxide SiO2 film on the surface of transparent optical material of glass or syntheic resin whose refractive indices are varied by changing the condition of vapor-deposition, under a predetermined condition of vapor-deposition so as to form a firm and durable anti-reflection film.

Method for coating anti-reflection film on surface of optical material

A reflection free optical glass coated, in succession, with a medium refractive index layer, such as CeF3 or Al2 O3, a high refractive index layer such as TiO2, CeO2 or ZrO2 which layer contains a plurality of thin layers of MgF2 of about 10-100A in thickness uniformly interposed in the high refractive index material at intervals of about one eighth of the design wavelength. The outermost coating of the multi-layer optical glass is a low refractive index layer of MgF2.

Anti reflection coating with a composite middle layer

A process for improving the property of the surface of an optical material by coating the surface with a mixture comprising 25 to 70% by weight of polyacrylic acid, 05 to 10% by weight of hexamethoxy methylmelamine, 01 to 2% by weight of aminopropyltriethoxysilane 001 to 01% by weight of polyethylene glycol fatty acid ester and 25 to 75% by weight of a solvent, drying and hardening the coating at a temperature of 50*C to 150*C

Hajime Kamiya

Papers

Method for coating anti-reflection film on surface of optical material

Anti reflection coating with a composite middle layer

Process for coating an optical material and the resulting product

Verfahren zum auftragen eines antireflexionsfilms auf die oberflaeche eines optischen koerpers