The invention discloses a method for preparing an Ag2O-TiO2 composite film through disodium EDTA (Ethylene Diamine Tetraacetic Acid) assisted ion exchange, and belongs to the technical field of nanometer material preparation. Aiming at the problems of low Ag2O deposition rate, uncontrollable process and poor deposited Ag2O particle uniformity in a current preparation method, the method comprises the steps of firstly preparing a TiO2 film containing a precursor ion on a titanium sheet matrix by utilizing a micro-arc oxidation technology in an electrolyte containing the precursor ion, wherein the precursor ion is the ion with the EDTA complexing stability constant being larger than an Ag ion; then soaking the prepared film into an Ag ion exchange solution, exchanging the precursor ion in thefilm with the Ag ion in the exchange solution, in-situ depositing the Ag ion to the surface of the TiO2 film, forming Ag2O nano-particles, and obtaining the nano Ag2O modified TiO2 heterojunction photocatalysis film. The method is simple and easily controlled in preparation process, convenient to operate and low in cost, and the film has high photocatalytic activity.

Method for preparing Ag2O-TiO2 composite film through disodium EDTA (Ethylene Diamine Tetraacetic Acid) assisted ion exchange

The invention discloses a preparation method of biopiezoelectric coating on titanium alloy surface. According to the preparation method of the biopiezoelectric coating on the titanium alloy surface, perovskite-structured nanotube coating is prepared on surface of titanium alloy by adopting an anodic oxidation method combined with hydrothermal reaction; and then, the perovskite-structured nanotubecoating is compounded with hydroxyapatite, thereby forming biopiezoelectric coating on the surface of the titanium alloy. The biopiezoelectric coating on the titanium alloy surface prepared by the preparation method has piezoelectric effects capable of promoting osteogenic differentiation, and is excellent in biological activity; and thus, the biopiezoelectric coating on the titanium alloy surfaceis capable of effectively accelerating bone repair process so as to shorten treatment cycle. Moreover, the biopiezoelectric coating on the titanium alloy surface can form effective osseointegration with tissues near the implantation site, thereby reducing risk of loosening.

Preparation method of biopiezoelectric coating on titanium alloy surface

The invention discloses a preparation method of a HA nano array bioactive coating. The preparation method comprises the following steps that firstly deionized water is taken as a solvent, sodium hydroxide is taken as a solute, alkali liquor is prepared, and a polished titanium sheet is soaked in the alkali liquor for pretreatment to obtain a net-shaped Na2Ti3O7 coating; then the deionized water istaken as a solvent, calcium salt and phosphorus salt are taken as solutes, the pH value of a solution after mixing is adjusted to be 11-12.5, then the net-shaped Na2Ti3O7 coating is put in the solution to react by utilizing a solvothermal method, and after the reaction is ended, the HA nano array bioactive coating is immediately obtained on the surface of a titanium alloy. According to the method, the hydroxyapatite nanorod coating with the good bioactivity is prepared on the surface of titanium by using a sodium hydroxide alkali liquor soaking-hydrothermal composite method, so that the experiment process is simplified, and the manufacturing cost is saved.

Preparation method of HA nano array bioactive coating

The invention belongs to the technical field of biomedical materials, and discloses an osteoinductive calcium phosphate ceramic with a hollow tube structure and a preparation method of the osteoinductive calcium phosphate ceramic. The problem of contradiction between osteoinductive optimization and mechanical strength improvement of calcium phosphate ceramic in the prior art is solved. The preparation method comprises the following steps: placing porous calcium phosphate ceramic in a neutral or alkaline phosphorus-containing solution, and carrying out hydrothermal reaction and heat treatment to obtain the osteoinductive calcium phosphate ceramic with the hollow tube structure on the surface. The osteoinductive calcium phosphate ceramic with the hollow tube structure has the advantages of scientific design, simple method and simplicity and convenience in operation, and the osteoinductive calcium phosphate ceramic with the hollow tube structure on the surface is obtained through hydrothermal treatment and heat treatment. The calcium phosphate ceramic with the hollow tube structure not only has excellent osteoinductive capacity, but also has better mechanical strength, and meets the requirements of clinical partial bearing bone defect repair and regeneration.

Osteoinductive calcium phosphate ceramic with hollow tube structure and preparation method of osteoinductive calcium phosphate ceramic

The invention discloses a structure-controllable magnetic response mineralized collagen coating used for the surface of a medical metal implant. The structure-controllable magnetic response mineralized collagen coating is constituted by mineralized collagen and Fe3O4 nanometer particles, wherein the Fe3O4 nanometer particles are distributed in the mineralized collagen. The structure-controllable magnetic response mineralized collagen coating adopts a magnetic field assisted alternate electric potential method; by adjusting parameters such as magnetic field strength in the composing and depositing process of an electrolyte, the nanometer magnetic particles are compounded into the mineralized collagen; and a modified layer with the magnetic response structure-controllable mineralized collagen is prepared on the surface of the metal implant. According to a preparation method of the structure-controllable magnetic response mineralized collagen coating, the structure-controllable magnetic response mineralized collagen coating is prepared through effective combination of an outer magnetic field and electrochemical deposition, the cell differentiation action is regulated and controlled, and the structure-controllable magnetic response mineralized collagen coating used for the surface of the medical metal implant has application prospects in restoration of hardbone tissue.

Structure-controllable magnetic response mineralized collagen coating used for surface of medical metal implant and preparation method thereof

The invention discloses a preparation method for an HA nano-tube bioactive coating layer The preparation method comprises the following steps: firstly, taking a titanium or titanium alloy sample as an anode and taking stainless steel as a cathode in an electrolyte containing calcium salt and phosphorus salt, carrying out micro-arc oxidation treatment on the titanium or titanium alloy sample through a pulse power supply, and generating a TiO2 coating layer on the surface layer of the titanium or titanium alloy sample after the reaction is concluded; secondly, carrying out primary hydrothermal reaction on the TiO2 coating layer in a strong base solution, and carrying out secondary hydrothermal reaction in a calcium-phosphorus solution after the reaction is concluded and cooling is carried out to obtain HA nano-rods; and finally, adjusting the pH value of an electrolyte taking a strong acid salt as a solute to achieve 1-4 through a strong acid in the electrolyte, taking the HA nano-rods as an anode, taking a platinum electrode as a cathode, carrying out electrochemical corrosion on the HA nano-rods through a constant-voltage power supply, that is, corroding the HA nano-rods along C-axis to obtain HA nano-tubes after the reaction is concluded The HA bioactive coating layer synthesised through the method disclosed by the invention is of a nano-tube-shaped structure, and is high in biocompatibility and bioactivity compared with titanium and the alloy thereof

Preparation method for HA nano-tube bioactive coating layer

The invention discloses a micro-arc oxidation preparation method of a magnetic TiO2 bioactive coating In an air environment, an electrolytic solution containing calcium salt, phosphor salt and molysite is taken, a pH value of the electrolytic solution is adjusted to be 50-53, titanium or a titanium alloy is taken as an anode, stainless steel is taken as a cathode, and titanium or the titanium alloy is subjected to micro-arc oxidation treatment for 1-8min by adopting a pulsed power supply, with the temperature of the electrolytic solution being kept at 5-25 DEG C, thus the magnetic TiO2 bioactive coating is generated on a surface layer of titanium or the titanium alloy The magnetic TiO2 coating having magnetism (Ms being 02696-1101emu/g) and good bioactivity can be prepared with the adoption of the micro-arc oxidation preparation method

Han Yong

Papers

Preparation method for HA nano-tube bioactive coating layer

Micro-arc oxidation preparation method of magnetic TiO2 bioactive coating