H
Hans P. Sauerwein
Researcher at University of Amsterdam
Publications - 155
Citations - 8032
Hans P. Sauerwein is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Insulin & Insulin resistance. The author has an hindex of 48, co-authored 155 publications receiving 7611 citations. Previous affiliations of Hans P. Sauerwein include Cho Ray Hospital & Valley Hospital.
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Journal ArticleDOI
Selective parasympathetic innervation of subcutaneous and intra-abdominal fat — functional implications
Felix Kreier,Eric Fliers,Peter J. Voshol,Corbert G. van Eden,Louis M. Havekes,Andries Kalsbeek,Caroline van Heijningen,Arja A. Sluiter,Thomas C. Mettenleiter,Johannes A. Romijn,Hans P. Sauerwein,Ruud M. Buijs +11 more
TL;DR: In this article, a rat was first sympathetically denervated and then injected with the retrograde transneuronal tracer pseudorabies virus (PRV), and the resulting labeling of PRV in the vagal motor nuclei of the brain stem reveals that adipose tissue receives vagal input.
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Noradrenaline inhibits lipopolysaccharide-induced tumor necrosis factor and interleukin 6 production in human whole blood.
TL;DR: In acute sepsis, enhanced release of noradrenaline may be part of a negative feedback mechanism meant to inhibit ongoing TNF and IL-6 production.
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Interleukin-6 stimulates coagulation, not fibrinolysis, in humans.
J. M. L. Stouthard,Marcel Levi,C. E. Hack,C.H.N. Veenhof,H. A. Romijn,Hans P. Sauerwein,T. van der Poll +6 more
TL;DR: It is concluded that in severe inflammation IL-6 may contribute to the activation of coagulation, whereas other factors mediate changes in fibrinolysis.
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Tumor Necrosis Factor: A Putative Mediator of the Sick Euthyroid Syndrome in Man
TL;DR: The results suggest that TNF is involved, either directly or indirectly, in the pathogenesis of the sick euthyroid syndrome.
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Endocrinologic and metabolic effects of interleukin-6 in humans.
J. M. L. Stouthard,Johannes A. Romijn,T. van der Poll,Erik Endert,S. Klein,Pieter J. Bakker,C. H. Veenhof,Hans P. Sauerwein +7 more
TL;DR: It is demonstrated that rhIL-6 induces many of the endocrinologic and metabolic changes found in catabolic states and thus may mediate some of the metabolic effects previously ascribed to other cytokines.