H
Hans Prengel
Researcher at Free University of Berlin
Publications - 11
Citations - 289
Hans Prengel is an academic researcher from Free University of Berlin. The author has contributed to research in topics: Triiodothyronine & Deiodinase. The author has an hindex of 10, co-authored 11 publications receiving 282 citations.
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Journal ArticleDOI
Elevated 3,5-Diiodothyronine Concentrations in the Sera of Patients with Nonthyroidal Illnesses and Brain Tumors
Graziano Pinna,Harald Meinhold,Luis Hiedra,Rudy Thoma,Thomas Hoell,Klaus-Jürgen Gräf,Gisela Stoltenburg-Didinger,Murat Eravci,Hans Prengel,Oliver Brödel,R. Finke,Andreas Baumgartner +11 more
TL;DR: A physiological, thyromimetic role of 3,5-T2, possibly stimulating mitochondrial respiratory chain activity may be one factor involved in maintaining clinical euthyroidism in patients with reduced serum levels of T3 during nonthyroidal illness.
Journal ArticleDOI
Rat Brain Type II 5′‐Iodothyronine Deiodinase Activity Is Extremely Sensitive to Stress
TL;DR: It is shown that even mild and very brief stress can induce marked increases in T3 concentrations specifically in brain but not in liver or blood, contrary to common opinion, thyroid hormones may play an important physiological role in stress reactions, at least in tissues that contain type II 5′‐iodothyronine deiodinase, such as brain and pituitary.
Journal ArticleDOI
Effects of lithium and carbamazepine on thyroid hormone metabolism in rat brain
Andreas Baumgartner,Graziano Pinna,Luis Hiedra,Ursula Gaio,Carsten Hessenius,Angel Campos-Barros,Murat Eravci,Hans Prengel,Rudy Thoma,Harald Meinhold +9 more
TL;DR: The effects of lithium (LI) and carbamazepine (CBM) on thyroid hormone metabolism were investigated in 11 regions of the brain and three peripheral tissues in rats decapitated at three different times of day, with results comparable with those seen in the prophylactic treatment of affective disorders.
3,3'-Diiodothyronine concentrations in the sera of patients with nonthyroidal illnesses and brain tumors and of healthy subjects during acute stress
Graziano Pinna,Luis Hiedra,Harald Meinhold,Murat Eravci,Hans Prengel,Oliver Brödel,Klaus Jürgen Gräf,Gisela Stoltenburg-Didinger,Michael Bauer,Andreas Baumgartner +9 more
TL;DR: In this paper, the authors describe the development of a highly sensitive, accurate, and reproducible RIA for the measurement of 3,3'-diiodothyronine (T 2 ) in human serum and brain tissue.
Journal ArticleDOI
3,3'-Diiodothyronine concentrations in the sera of patients with nonthyroidal illnesses and brain tumors and of healthy subjects during acute stress.
Graziano Pinna,Luis Hiedra,Harald Meinhold,Murat Eravci,Hans Prengel,Oliver Brödel,Klaus Jürgen Gräf,Gisela Stoltenburg-Didinger,Michael Bauer,Andreas Baumgartner +9 more
TL;DR: The results show that, contrary to expectation, a low T3 syndrome in NTI is not always associated with low serum concentrations of 3,3'-T2 and, in healthy controls, 2 different forms of acute stress significantly increased serum levels of T4 and T3, but did not affect those of 2,4-T1 or 3,5-T2.