H
Haruaki Yamamoto
Researcher at Bristol-Myers Squibb
Publications - 26
Citations - 774
Haruaki Yamamoto is an academic researcher from Bristol-Myers Squibb. The author has contributed to research in topics: Actinomadura & Antifungal antibiotic. The author has an hindex of 15, co-authored 26 publications receiving 732 citations.
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Journal ArticleDOI
Epoxomicin, a new antitumor agent of microbial origin.
Minoru Hanada,Koko Sugawara,Keiko Kaneta,Soichiro Toda,Yuji Nishiyama,Koji Tomita,Haruaki Yamamoto,Masataka Konishi,Toshikazu Oki +8 more
TL;DR: An actinomycete strain No.
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TERPESTACIN, A NEW SYNCYTIUM FORMATION INHIBITOR FROM Arthrinium sp.
Masahisa Oka,Seiji Iimura,Osamu Tenmyo,Yosuke Sawada,Masaru Sugawara,Noriyuki Ohkusa,Haruaki Yamamoto,Kimio Kawano,Shiu-Lok Hu,Yasuo Fukagawa,Toshikazu Oki +10 more
TL;DR: The structure of terpestacin was elucidated as a bicyclic sesterterpene on the basis of spectroscopic data and chemical derivatization.
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Pradimicins A, B and C: new antifungal antibiotics. I. Taxonomy, production, isolation and physico-chemical properties.
Koji Tomita,Maki Nishio,Kyoichiro Saitoh,Haruaki Yamamoto,Yutaka Hoshino,Hiroaki Ohkuma,Masataka Konishi,Takeo Miyaki,Toshikazu Oki +8 more
TL;DR: New antifungal antibiotics, pradimicins A, B and C were isolated from the culture broth of actinomycete strains proposed as Actinomadura hibisca, containing orange to red pigments containing a benzo[a]naphthacenequinone chromophore substituted with a D-alanine, an aminosugar and aD-xylose.
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Melanostatin, a new melanin synthesis inhibitor. Production, isolation, chemical properties, structure and biological activity.
Yasumasa Ishihara,Masahisa Oka,Mitsuaki Tsunakawa,Koji Tomita,Masami Hatori,Haruaki Yamamoto,Hideo Kamei,Takeo Miyaki,Masataka Konishi,Toshikazu Oki +9 more
TL;DR: Melanostatin, a new antibiotic with melanin synthesis inhibitor activity, was isolated from the fermentation broth of Streptomyces clavifer No.
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New antifungal antibiotics pradimicins FA-1 and FA-2: D-serine analogs of pradimicins A and C.
TL;DR: The new pradimicin analogs share a common core structure of 5,6-dihydrobenzo[a]naphthacenequinone substituted by D-serine, but differ in the disaccharide moiety at C-5, and have an N-methylamino sugar and D-xylose.