H
Hasan Ilkova
Researcher at Joslin Diabetes Center
Publications - 1
Citations - 549
Hasan Ilkova is an academic researcher from Joslin Diabetes Center. The author has contributed to research in topics: Cellular differentiation & Islet. The author has an hindex of 1, co-authored 1 publications receiving 533 citations.
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Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes.
Jean-Christophe Jonas,Arun Sharma,Wendy M. Hasenkamp,Hasan Ilkova,Giovanni Patané,Ross Laybutt,Susan Bonner-Weir,Gordon C. Weir +7 more
TL;DR: Chronic hyperglycemia leads to β cell hypertrophy and loss of β cell differentiation that is correlated with changes in c-Myc and other key transcription factors, which could contribute to the profound derangement of insulin secretion in human diabetes.