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Heather E. Connally

Researcher at Colorado State University

Publications -  9
Citations -  202

Heather E. Connally is an academic researcher from Colorado State University. The author has contributed to research in topics: Ethylene glycol & Fomepizole. The author has an hindex of 7, co-authored 9 publications receiving 188 citations.

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Journal ArticleDOI

Cytology and fluid analysis of the acute abdomen

TL;DR: In patients with acute abdominal pain, abdominal paracentesis and diagnostic peritoneal lavage often yield fluid samples for cytologic and biochemical evaluation, which can be a crucial tool for the rapid diagnosis necessary for initiation of timely and appropriate therapy.
Journal Article

Safety and efficacy of 4-methylpyrazole for treatment of suspected or confirmed ethylene glycol intoxication in dogs : 107 cases (1983-1995)

TL;DR: 4-MP was a safe and effective treatment for EG intoxication when it was given before sufficient quantities of EG had been metabolized to induce renal failure and dogs treated within 8 hours of EG ingestion had a good prognosis.
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Effects of dietary cholesterol restriction in a feline model of Niemann-Pick type C disease.

TL;DR: Although some hepatic parameters were modified, dietary cholesterol restriction did not appear to alter disease progression in NPC-affected kittens, and Histological findings in liver sections showed a diffuse uniform microvacuolar pattern within hepatocytes and Kupffer cells, in contrast to a heterogeneous macro/microvacUolar pattern and prominent nodular fibrosis in NPCs.
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Safety and efficacy of high-dose fomepizole compared with ethanol as therapy for ethylene glycol intoxication in cats.

TL;DR: Fomepizole is safe when administered to cats in high doses, prevents EG-induced fatal ARF when therapy is instituted within 3 hours of EG ingestion, and is more effective than treatment with EtOH.
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Inhibition of canine and feline alcohol dehydrogenase activity by fomepizole

TL;DR: Feline ADH has lower enzymatic capacity for turnover or is less concentrated in liver than canine ADH with regard to EtOH and EG catalysis, and higher dosages of fomepizole may be more effective to treat cats with EG intoxication than dosages reported to treat dogs.