This invention relates to the design and function of a compressible valve replacement prosthesis, collared or uncollared, which can be deployed into a beating heart without extracorporeal circulation using a transcatheter delivery system. The design as discussed focuses on the deployment of a device via a minimally invasive fashion and by way of example considers a minimally invasive surgical procedure preferably utilizing the intercostal or subxyphoid space for valve introduction. In order to accomplish this, the valve is formed in such a manner that it can be compressed to fit within a delivery system and secondarily ejected from the delivery system into the annulus of a target valve such as a mitral valve or tricuspid valve.

Prosthetic valves and related inventions

This invention relates to the design and function of a device which allows for retrieval of a previously implanted valve prosthesis from a beating heart without extracorporeal circulation using a transcatheter retrieval system, including a guide component to facilitate the compression of the valve and retraction into a retrieval catheter, as well as an improved prosthetic transcatheter heart valve having one or more of: a series of radially extending tines having a loop terminus to improve sealing a deployed prosthetic mitral valve against hemodynamic leaking, a pre-compressible stent-in-stent design, or an articulating cuff attached to a covered stent-valve and a commissural sealing skirt structure attached to the underside of the articulating cuff.

Multi-component designs for heart valve retrieval device, sealing structures and stent assembly

This invention relates to the design and function of a single-tether compressible valve replacement prosthesis which can be deployed into a beating heart without extracorporeal circulation using a transcatheter delivery system. The design as discussed combats the process of wear on anchoring tethers over time by using a plurality of stent-attached, centering tethers, which are themselves attached to a single anchoring tether, which extends through the ventricle and is anchored to a securing device located on the epicardium.

Tethers for prosthetic mitral valve

A heart valve stent having a section with a heart valve implant and several proximally disposed tissue anchors, also comprising a plurality of anchoring threats, each with a proximate end fastened to the stent or valve and a distal end attached to tissue within a heart chamber to provide tension between the heart chamber tissue and the stent.

Truncated cone heart valve stent

Various embodiments of an apparatus, system, and method are disclosed for reducing NO x emissions on an SCR catalyst. For example, according to one representative embodiment, an apparatus for reducing NO x emissions in an engine exhaust includes a NO x reduction target module that is configured to determine a NO x reduction requirement that includes an amount of NO x in the exhaust gas stream to be reduced on a selective catalytic reduction (SCR) catalyst. The apparatus also includes an ammonia target module that is configured to determine an ammonia addition requirement that includes an amount of ammonia added to the exhaust gas stream to achieve the NO x reduction requirement. The apparatus also includes a reductant target module that is configured to determine a reductant injection requirement that includes an amount of reductant added to the exhaust gas stream to achieve the ammonia addition requirement. The apparatus further includes a reductant limiting module that is configured to determine whether at least one reductant limiting condition is met and to limit the amount of reductant added in response to the at least one reductant limiting condition if the at least one reductant limiting condition has been met.

APPARATUS, SYSTEM, AND METHOD FOR REDUCING NOx EMISSIONS ON AN SCR CATALYST

A method of controlling a rate of introduction of a NOx reducing substance or precursor to a catalyst component (1). The method comprises obtaining the amount of NOx entering the catalyst component (1), modelling the amount of NOx reducing substance or precursor in the catalyst component (1) and controlling the rate of introduction of the NOx reducing substance or precursor to reduce NOx.

Hector Sindano

Papers

Control of selective catalytic reduction