H
Heinrich M. Schulte
Researcher at National Institutes of Health
Publications - 66
Citations - 5610
Heinrich M. Schulte is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Corticotropin-releasing hormone & Pituitary gland. The author has an hindex of 37, co-authored 66 publications receiving 5493 citations. Previous affiliations of Heinrich M. Schulte include Boston Children's Hospital & University of Kiel.
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Journal ArticleDOI
Molecular Determinants of Glucocorticoid Receptor Function and Tissue Sensitivity to Glucocorticoids
TL;DR: This review has summarized the multiple endogenous and exogenous factors that have been shown to be involved in this signaling cascade and, thus, to alter glucocorticoid sensitivity.
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Dehydroepiandrosterone replacement in women with adrenal insufficiency.
Wiebke Arlt,Frank Callies,J C van Vlijmen,Ines Koehler,Martin Reincke,Martin Bidlingmaier,Doris Dr Huebler,Michael Oettel,Michael Ernst,Heinrich M. Schulte,Bruno Allolio +10 more
TL;DR: Dehydroepiandrosterone improves well-being and sexuality in women with adrenal insufficiency and significantly improved overall well- being as well as scores for depression and anxiety.
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The corticotropin-releasing factor stimulation test. An aid in the evaluation of patients with Cushing's syndrome.
George P. Chrousos,Heinrich M. Schulte,Edward H. Oldfield,Phillip W. Gold,Gordon B. Cutler,D. L. Loriaux +5 more
TL;DR: Investigation of the effect of exogenous corticotropin-releasing factor on plasma levels of ACTH and cortisol in patients with ACTH-secreting pituitary adenomas and other forms of Cushing's syndrome concludes that stimulation of the pituitaries-adrenal axis with corticotropic factor may be useful in differentiating pituitsary from ectopic causes of Cushed's syndrome.
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Preoperative lateralization of ACTH-secreting pituitary microadenomas by bilateral and simultaneous inferior petrosal venous sinus sampling.
Edward H. Oldfield,George P. Chrousos,Heinrich M. Schulte,M Schaaf,McKeever Pe,A G Krudy,Gordon B. Cutler,D. L. Loriaux,J L Doppman +8 more
TL;DR: The utility of selective catheterization of the inferior petrosal sinus for determination of plasma ACTH concentrations in the diagnosis of pituitary-dependent hypercortisolism is established and simultaneous sampling of bilateral venous blood should provide a means of localizing the microadenoma in one side of the pituitaries.
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Oral Dehydroepiandrosterone for Adrenal Androgen Replacement: Pharmacokinetics and Peripheral Conversion to Androgens and Estrogens in Young Healthy Females after Dexamethasone Suppression
Wiebke Arlt,Hans-Georg Justl,Frank Callies,Martin Reincke,Doris Hübler,Michael Oettel,Michael Ernst,Heinrich M. Schulte,Bruno Allolio +8 more
TL;DR: 50 mg DHEA seems to be a suitable replacement dose in females with adrenal insufficiency, and the rapid and lasting conversion to potent androgens demonstrates a potential role of D HEA for androgen replacement in females in general.