H
Heinrich M. Schulte
Researcher at National Institutes of Health
Publications - 66
Citations - 5610
Heinrich M. Schulte is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Corticotropin-releasing hormone & Pituitary gland. The author has an hindex of 37, co-authored 66 publications receiving 5493 citations. Previous affiliations of Heinrich M. Schulte include Boston Children's Hospital & University of Kiel.
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Journal ArticleDOI
Corticotropin-Releasing Factor: Pharmacokinetics in Man
Heinrich M. Schulte,George P. Chrousos,J. D. Booth,Edward H. Oldfield,Philip W. Gold,Gordon B. Cutler,D. Lynn Loriaux +6 more
TL;DR: The relatively low MCR of CRF may explain its prolonged biological action in primates and man and its pharmacokinetic parameters in man.
Journal ArticleDOI
The effects of corticotropin releasing factor on the anterior pituitary function of stalk-sectioned cynomdlgus macaques: Dose response of cortisol secretion
Heinrich M. Schulte,George P. Chrousos,Edward H. Oldfield,Phillip W. Gold,Gordon B. Cutler,D. L. Loriaux +5 more
TL;DR: The recent identification of ovine corticotropin releasing factor (CRF), a 41-amino acid peptide, provides a potential new approach to evaluate disorders of the hypothalamic-pituitary-adrenal axis.
Journal ArticleDOI
Corticotropin-releasing factor stimulation test.
George P. Chrousos,Heinrich M. Schulte,Edward H. Oldfield,Philip W. Gold,Gordon B. Cutler,D. Lynn Loriaux +5 more
TL;DR: Investigation of the effect of exogenous corticotropin-releasing factor on plasma levels of ACTH and Cortisol in 13 patients with ACTH-secreting pituitary adenomas and in 9 patients with other forms of Cushing's syndrome found no difference in responsiveness between these two patient groups.
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Ovine corticotropin-releasing factor administration in normal men. Pituitary and adrenal responses in the morning and evening.
Heinrich M. Schulte,George P. Chrousos,Edward H. Oldfield,Phillip W. Gold,Gordon B. Cutler,D. L. Loriaux +5 more
TL;DR: It is indicated that the magnitude of the plasma cortisol rise after CRF depends on the time of administration, and that the influence of circadian changes in the hypothalamic-pituitary-adrenal axis on the response to CRF is influenced by these changes.
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Nonhypnotic low-dose etomidate for rapid correction of hypercortisolaemia in Cushing's syndrome.
TL;DR: It is concluded that low-dose non-hypnotic etomidate reduces serum cortisol to within the normal range in patients with Cushing's syndrome and may become the drug of choice for rapid initial control of hypercortisolism.