H
Henrike M. Hamer
Researcher at Maastricht University
Publications - 23
Citations - 3141
Henrike M. Hamer is an academic researcher from Maastricht University. The author has contributed to research in topics: Butyrate & Internal medicine. The author has an hindex of 11, co-authored 17 publications receiving 2662 citations.
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Journal ArticleDOI
Review article: the role of butyrate on colonic function
Henrike M. Hamer,Daisy Jonkers,Koen Venema,Steven Vanhoutvin,Freddy J. Troost,Robert Brummer +5 more
TL;DR: Butyrate is an important energy source for intestinal epithelial cells and plays a role in the maintenance of colonic homeostasis, and is a main end‐product of intestinal microbial fermentation of mainly dietary fibre.
Journal ArticleDOI
Butyrate modulates oxidative stress in the colonic mucosa of healthy humans
Henrike M. Hamer,Daisy Jonkers,Aalt Bast,Steven Vanhoutvin,Marc A. J. G. Fischer,Andrea Kodde,Freddy J. Troost,Koen Venema,Robert-Jan M. Brummer,Robert-Jan M. Brummer +9 more
TL;DR: It is demonstrated that butyrate is able to beneficially affect oxidative stress in the healthy human colon.
Journal ArticleDOI
Butyrate-induced transcriptional changes in human colonic mucosa
Steven Vanhoutvin,Freddy J. Troost,Henrike M. Hamer,Patrick J. Lindsey,Ger H. Koek,Daisy Jonkers,Andrea Kodde,Koen Venema,Robert Brummer,Robert Brummer +9 more
TL;DR: Colonic administration of butyrate in concentrations that can be achieved by consumption of a high-fiber diet enhances the maintenance of colonic homeostasis in healthy subjects, by regulating fatty acid metabolism, electron transport and oxidative stress pathways on the transcriptional level.
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Effect of butyrate enemas on inflammation and antioxidant status in the colonic mucosa of patients with ulcerative colitis in remission
Henrike M. Hamer,Daisy Jonkers,S.A.L.W. Vanhoutvin,Freddy J. Troost,Ger T. Rijkers,Adriaan P. de Bruïne,Aalt Bast,Koen Venema,Robert-Jan M. Brummer,Robert-Jan M. Brummer +9 more
TL;DR: Although UC patients in remission were characterized by low-grade oxidative stress and inflammation, rectal butyrate enemas showed only minor effects on inflammatory and oxidative stress parameters.
Journal ArticleDOI
The effects of butyrate enemas on visceral perception in healthy volunteers.
Steven Vanhoutvin,Freddy J. Troost,T. O. C. Kilkens,Patrick J. Lindsey,Henrike M. Hamer,Daisy Jonkers,Koen Venema,Robert Brummer,Robert Brummer +8 more
TL;DR: Colonic administration of butyrate, at physiologically relevant concentrations, dose‐dependently decreases visceral sensitivity in healthy volunteers.