H
Hernan A. Orgueira
Researcher at Massachusetts Institute of Technology
Publications - 10
Citations - 520
Hernan A. Orgueira is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Iduronic acid & Catalysis. The author has an hindex of 8, co-authored 10 publications receiving 487 citations.
Papers
More filters
Journal ArticleDOI
Modular Synthesis of Heparin Oligosaccharides
Hernan A. Orgueira,Alessandra Bartolozzi,Peter Schell,Remy E. J. N. Litjens,Remy E. J. N. Litjens,Emma R. Palmacci,Peter H. Seeberger +6 more
TL;DR: A general, modular strategy for the first completely stereoselective synthesis of defined heparin oligosaccharides is described, and the union of many glucosamine uronic acid disaccharide modules did not meet any problems, certain sequences proved not accessible.
Journal ArticleDOI
Regioselective synthesis of [1,2,3]-triazoles catalyzed by Cu(I) generated in situ from Cu(0) nanosize activated powder and amine hydrochloride salts
TL;DR: In this article, a straightforward and efficient method for the regioselective synthesis of functionalized 1,4 disubstituted [1,2,3]-triazoles, from terminal alkynes and azides, has been established utilizing Cu(0) as the source of the catalytic species.
Journal ArticleDOI
Conformational locking of the glycosyl acceptor for stereocontrol in the key step in the synthesis of heparin.
Journal ArticleDOI
Synthesis and transformations of D-glucuronic and L-iduronic acid glycals
TL;DR: Both d -glucuronic and l -iduronic acid glycals were transformed into glycosylating agents for use in the synthesis of glycosaminoglycan oligosaccharides.
Journal ArticleDOI
Cover Picture: Chem. Eur. J. 1/2003
Hernan A. Orgueira,Alessandra Bartolozzi,Peter Schell,Remy E. J. N. Litjens,Remy E. J. N. Litjens,Emma R. Palmacci,Peter H. Seeberger +6 more
TL;DR: Seeberger et al. as discussed by the authors proposed a completely stereoselective synthesis of defined heparin oligosaccharides by placing a conformational constraint on uronic acid glycosyl acceptors.