H
Hidekazu Ouchi
Researcher at Kindai University
Publications - 8
Citations - 25
Hidekazu Ouchi is an academic researcher from Kindai University. The author has contributed to research in topics: Williamson ether synthesis & Moiety. The author has an hindex of 3, co-authored 8 publications receiving 21 citations.
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Structure–activity relationships of flavanones, flavanone glycosides, and flavones in anti-degranulation activity in rat basophilic leukemia RBL-2H3 cells
TL;DR: The structure–activity relationships of flavonoids in their degranulation-inhibiting activity have not been systematically characterized and the information obtained may guide the development of a therapy for type I allergies.
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Synthesis and degranulation-inhibiting activities of the proposed apteniols B, C, and G.
Toshiro Noshita,Akihiro Tai,Hikaru Nishikawa,Kaoru Ikeda,Hidekazu Ouchi,Yoshitomo Hamada,Akiko Saito,Teiko Yamada +7 more
TL;DR: The synthesis of compounds with the structures proposed for the oxyneolignan apteniols B, C, and G did not agree with those of isolated compounds and did not show degranulation-inhibiting activity.
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Synthetic and in vitro studies to indicate that the structure of the PTP1B inhibitor isolated from Acanthopanax senticosus requires reinvestigation
Toshiro Noshita,Ryoya Onishi,Kaori Miura,Yoshitomo Hamada,Yuki Nishino,Hidekazu Ouchi,Akihiro Tai +6 more
TL;DR: In this article, the synthesis of 3,5-dimethoxy-4-{2-methoxy]-4-[(1E)-3-oxoprop-1-en-1yl]benzaldehyde (1) (the proposed structure for the naturally occurring protein tyrosine phosphatase 1B) inhibitor isolated from Acanthopanax senticosus) and its three positional isomers 3, 4, and 5.
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Syntheses and biological activities of the proposed structure of apteniol A and its derivatives
Hikaru Nishikawa,Toshiro Noshita,Akihiro Tai,Hidekazu Ouchi,Taisuke Okamoto,Akiko Saito,Teiko Yamada,Atsuko Iomori,Nao Ishimata +8 more
TL;DR: The dimethyl ester derivative of the proposed apteniol A was found to enhance neurite outgrowth in PC12 cells and inhibit antigen-induced degranulation in RBL-2H3 cells.
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The structure proposed for apteniol D is different from that of the compound obtained by total synthesis
Toshiro Noshita,Kohei Matsumoto,Hikaru Nishikawa,Hidekazu Ouchi,Yoshitomo Hamada,Akiko Saito,Teiko Yamada +6 more
TL;DR: The synthesis of 4,4′-oxyneolignan, the proposed structure for naturally occurring apteniol D, was formed via classical Ullmann ether synthesis using excess copper powder in N,N-dimethylacetamide.