H
Hideo Otani
Researcher at Kyoto University
Publications - 26
Citations - 1332
Hideo Otani is an academic researcher from Kyoto University. The author has contributed to research in topics: Cholesteryl ester & Cholesterol. The author has an hindex of 16, co-authored 26 publications receiving 1254 citations. Previous affiliations of Hideo Otani include Hokkaido University.
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Journal ArticleDOI
Exercise Stress Test Amplifies Genotype-Phenotype Correlation in the LQT1 and LQT2 Forms of the Long-QT Syndrome
Kotoe Takenaka,Tomohiko Ai,Wataru Shimizu,Atsushi Kobori,Tomonori Ninomiya,Hideo Otani,Tomoyuki Kubota,Hiroshi Takaki,Shiro Kamakura,Minoru Horie +9 more
TL;DR: Tpe interval increases during exercise in L QT1 but not in LQT2, which may partially account for the finding that fatal cardiac events in LqT1 are more often associated with exercise.
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Drug-Induced Long-QT Syndrome Associated With a Subclinical SCN5A Mutation
Naomasa Makita,Minoru Horie,Takeshi Nakamura,Tomohiko Ai,Koji Sasaki,Hisataka Yokoi,Masayuki Sakurai,Ichiro Sakuma,Hideo Otani,Hirofumi Sawa,Akira Kitabatake +10 more
TL;DR: This study demonstrates that subclinical mutations in the LQTS-related gene SCN5A may predispose certain individuals to drug-induced cardiac arrhythmias.
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Elevated Basic Fibroblast Growth Factor in Pericardial Fluid of Patients With Unstable Angina
Masatoshi Fujita,Masaki Ikemoto,Masamichi Kishishita,Hideo Otani,Ryuji Nohara,Terumitsu Tanaka,Shunichi Tamaki,Ario Yamazato,Shigetake Sasayama +8 more
TL;DR: This finding provides new evidence that bFGF plays an important role in mediating collateral growth in humans.
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Regulation of apolipoprotein B production and secretion in response to the change of intracellular cholesteryl ester contents in rabbit hepatocytes.
Makoto Tanaka,Hisato Jingami,Hideo Otani,Mikimaro Cho,Yukihiko Ueda,Hiroshi Arai,Yutaka Nagano,Toshio Doi,Masayuki Yokode,Toru Kita +9 more
TL;DR: It is concluded that intracellular cholesteryl ester contents play a critical role in apolipoprotein B-100 secretion, and the intrACEllular apoB degradation rate could be the main mechanism that regulates apo B secretion in response to the change of intrace cellular cholesterol ester level.
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Novel KCNJ2 Mutation in Familial Periodic Paralysis With Ventricular Dysrhythmia
Tomohiko Ai,Yuichiro Fujiwara,Keiko Tsuji,Hideo Otani,Shozo Nakano,Yoshihiro Kubo,Minoru Horie +6 more
TL;DR: T192, which is located in the phosphatidylinositol-4,5-bisphosphate binding site and also the region necessary for Kir2.1 multimerization, is a highly conserved amino acid residue among inward-rectifier channels.