H
Hikaru Fujioka
Researcher at Nagasaki University
Publications - 97
Citations - 1341
Hikaru Fujioka is an academic researcher from Nagasaki University. The author has contributed to research in topics: Transplantation & Hepatectomy. The author has an hindex of 19, co-authored 96 publications receiving 1194 citations. Previous affiliations of Hikaru Fujioka include Saga Group.
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Journal ArticleDOI
Human intrahepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kappaB and -MAPK signaling pathways.
Terufumi Yokoyama,Atsumasa Komori,Minoru Nakamura,Yasushi Takii,Takashi Kamihira,Shinji Shimoda,Tsuyoshi Mori,Shinsuke Fujiwara,Makiko Koyabu,Ken Taniguchi,Hikaru Fujioka,Kiyoshi Migita,Hiroshi Yatsuhashi,Hiromi Ishibashi +13 more
TL;DR: Human intrahepatic biliary epithelial cells may play active roles in both the innate and adaptive immune responses, and the role of toll‐like receptors (TLRs) on HIBECs in inflammatory cholangiopathies is unknown.
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Enhanced expression of type I interferon and toll-like receptor-3 in primary biliary cirrhosis.
Yasushi Takii,Minoru Nakamura,Masahiro Ito,Terufumi Yokoyama,Atsumasa Komori,Yuki Shimizu-Yoshida,Rumiko Nakao,Koichiro Kusumoto,Shinya Nagaoka,Koji Yano,Seigo Abiru,Toshihito Ueki,Takehiro Matsumoto,Manabu Daikoku,Ken Taniguchi,Hikaru Fujioka,Kiyoshi Migita,Hiroshi Yatsuhashi,Masahiro Nakashima,Mine Harada,Hiromi Ishibashi +20 more
TL;DR: expression levels of type I IFN and TLR-3 mRNAs were significantly higher in portal tract and liver parenchyma as compared to AIH and CHC and form the basis for the hypothesis that these signaling pathways are involved in the pathophysiology of PBC.
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Regression of Hepatocellular Carcinoma in Vitro and in Vivo by Radiosensitizing Suicide Gene Therapy under the Inducible and Spatial Control of Radiation
Yujo Kawashita,Akira Ohtsuru,Yasufumi Kaneda,Yuji Nagayama,Yasushi Kawazoe,Susumu Eguchi,Hiroaki Kuroda,Hikaru Fujioka,Masahiro Ito,Takashi Kanematsu,Shunichi Yamashita +10 more
TL;DR: The data indicate that HSV-tk gene therapy under the control of a radioinducible promoter is effective, and might be selective for hepatoma cells because of its inducible and radiosensitive capacity after radiation exposure as well as its tumor-specific activation.
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Total thyroidectomy versus thyroid lobectomy for papillary thyroid cancer: Comparative analysis after propensity score matching: A multicenter study
Sayaka Kuba,Kosho Yamanouchi,Naomi Hayashida,Shigeto Maeda,Toshiyuki Adachi,Chika Sakimura,Fusako Kawakami,Hiroshi Yano,Megumi Matsumoto,Ryota Otsubo,Shuntaro Sato,Hikaru Fujioka,Tamotsu Kuroki,Takeshi Nagayasu,Susumu Eguchi +14 more
TL;DR: Equivalent prognoses were observed for patients with 1- to 5-cm stage cN0 and cM0 PTC tumors treated by TL or TT after propensity score matching, and adverse events occurred less frequently in patients who underwent TL than TT.
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Impact of Anatomical Resection for Hepatocellular Carcinoma With Microportal Invasion (vp1): A Multi-institutional Study by the Kyushu Study Group of Liver Surgery.
Masaaki Hidaka,Susumu Eguchi,Koji Okuda,Toru Beppu,Ken Shirabe,Kazuhiro Kondo,Yuko Takami,Masayuki Ohta,Masayuki Shiraishi,Shinichi Ueno,Atsushi Nanashima,Tomoaki Noritomi,Kenji Kitahara,Hikaru Fujioka +13 more
TL;DR: Although local recurrence around the resection site was suppressed by AR, AR for HCC with vp1 did not influence the RFS or OS rates after hepatectomy in the modern era.