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Hisateru Takano

Researcher at Ibaraki University

Publications -  190
Citations -  2069

Hisateru Takano is an academic researcher from Ibaraki University. The author has contributed to research in topics: Ventricular assist device & Blood pump. The author has an hindex of 24, co-authored 190 publications receiving 2030 citations.

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Evaluation of Microencapsulated Islets in Agarose Gel as Bioartificial Pancreas by Studies of Hormone Secretion in Culture and by Xenotransplantation

TL;DR: Hamster islets in groups of 400–1000 encapsulated in microbeads containing 11–14% (wt/wt) agarose were xenogenically transplanted into the peritoneal cavity of five diabetic mice and secreted insulin into the culture medium and could rapidly increase their insulin release in response to a glucose challenge even after >100 days.
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Influence of prolonged ventricular assistance on myocardial histopathology in intact heart.

TL;DR: The results indicate that long-term ventricular assistance in the intact heart leads to myocardial atrophy, and suggests that in the damaged heart subjected to prolonged unloading by Ventricular assistance, there is the possibility of limiting compensatory hypertrophic changes in the residual intact myocardium.
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Fatty acid myocardial imaging using 123I-β-methyl-iodophenyl pentadecanoic acid (BMIPP): comparison of myocardial perfusion and fatty acid utilization in canine myocardial infarction (Occlusion and reperfusion model)

TL;DR: The findings indicate that the combination of BMIPP and thallium for myocardial imaging supply different information about the zone of infarction and ischemia, which may be useful for the assessment of myocardIAL viability.
Journal Article

Cardiac disuse atrophy during LVAD pumping.

TL;DR: It is indicated that LVADs cause cardiac atrophy which correlates with bypass flow rate and duration of assistance, and relative volume density of myofibrils was reduced in the maximum and 90 day bypass groups.
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Development of design methods of a centrifugal blood pump with in vitro tests, flow visualization, and computational fluid dynamics: results in hemolysis tests.

TL;DR: Investigation of the relationship between hemolysis and flow patterns in centrifugal blood pumps revealed that small gaps led to more hemolytic performances and that the backward type vane caused morehemolysis, therefore, the design parameters of centrifugalBlood pumps could affect their hemolytics performances.