H
Hong H. Chang
Researcher at Gyeongsang National University
Publications - 9
Citations - 203
Hong H. Chang is an academic researcher from Gyeongsang National University. The author has contributed to research in topics: Proinflammatory cytokine & Interleukin 10. The author has an hindex of 7, co-authored 9 publications receiving 157 citations.
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Journal ArticleDOI
Chicken IL-17F: identification and comparative expression analysis in Eimeria-infected chickens.
Woo H. Kim,Jipseol Jeong,Ae R. Park,Dongjean Yim,Yong-Hwan Kim,Kwang D. Kim,Hong H. Chang,Hyun S. Lillehoj,Byung-Hyung Lee,Wongi Min +9 more
TL;DR: Results suggest that chIL-17F is a unique member of the IL-17 family of cytokine, which plays an important role in gut homeostasis.
Journal ArticleDOI
Activation of NF-kB-Mediated TNF-Induced Antimicrobial Immunity Is Required for the Efficient Brucella abortus Clearance in RAW 264.7 Cells.
Huynh Tan Hop,Alisha Wehdnesday Bernardo Reyes,Tran Xuan Ngoc Huy,Lauren Togonon Arayan,Wongi Min,Hu J. Lee,Man H. Rhee,Hong H. Chang,Suk Kim +8 more
TL;DR: It is shown that infection of macrophage with B. abortus induces marked expression and secretion of TNF which subsequently binds to TNF receptor 1 (TNFR-1) and activates a downstream signaling cascade of the innate immunity.
Journal ArticleDOI
The Key Role of c-Fos for Immune Regulation and Bacterial Dissemination in Brucella Infected Macrophage.
Huynh Tan Hop,Lauren Togonon Arayan,Tran Xuan Ngoc Huy,Alisha Wehdnesday Bernardo Reyes,Son Hai Vu,Wongi Min,Hu J. Lee,Man H. Rhee,Hong H. Chang,Suk Kim +9 more
TL;DR: The suppression of c-Fos signaling by siRNA treatment resulted in significant induction of TLR4, which subsequently activates p38 and ERK1/2 mitogen-activated protein kinases (MAPKs) and enhances F-actin polymerization, leading to an increase in B. abortus phagocytosis.
Journal ArticleDOI
Downregulation of Chicken Interleukin-17 Receptor A during Eimeria Infection
Woo H. Kim,Jipseol Jeong,Ae R. Park,Dongjean Yim,Suk Kim,Hong H. Chang,Seung-Hak Yang,Dong Hee Kim,Hyun S. Lillehoj,Wongi Min +9 more
TL;DR: The results suggest that chIL-17RA has an important role in mucosal immunity to intestinal intracellular parasite infections such as Eimeria infection.
Journal ArticleDOI
Monoclonal antibodies reactive with chicken interleukin-17
Jeongmi Yoo,Hong H. Chang,Yeong H. Bae,Chi-Nam Seong,Nong-Hoon Choe,Hyun S. Lillehoj,Jong-Hyeon Park,Wongi Min +7 more
TL;DR: Results indicate that these new monoclonal antibodies are specific for chIL-17 and will be a useful tool for structural and immunological studies of IL-17 in poultry.