H
Hsin Ping Chiu
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 1
Citations - 135
Hsin Ping Chiu is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Innate immune system & Proteases. The author has an hindex of 1, co-authored 1 publications receiving 32 citations.
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SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species.
Mehdi Moustaqil,Emma Ollivier,Hsin Ping Chiu,Sarah van Tol,Paulina Rudolffi-Soto,Christian S. Stevens,Akshay Bhumkar,Dominic J. B. Hunter,Dominic J. B. Hunter,Alexander N. Freiberg,David A. Jacques,Benhur Lee,Emma Sierecki,Yann Gambin +13 more
TL;DR: New functions of the NSP3 and NSP5 proteases of SARS-CoV-2 are discovered, demonstrating that they could directly cleave proteins involved in the host innate immune response, providing an explanatory framework for indepth studies into the pathophysiology of COVID-19.