H
Hua Yun Chen
Researcher at University of Illinois at Chicago
Publications - 33
Citations - 1450
Hua Yun Chen is an academic researcher from University of Illinois at Chicago. The author has contributed to research in topics: Estimator & Missing data. The author has an hindex of 16, co-authored 28 publications receiving 1280 citations.
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Journal ArticleDOI
Female Genital-Tract HIV Load Correlates Inversely with Lactobacillus Species but Positively with Bacterial Vaginosis and Mycoplasma hominis
Beverly E. Sha,M. Reza Zariffard,Qiong J. Wang,Hua Yun Chen,James W. Bremer,Mardge H. Cohen,Gregory T. Spear +6 more
TL;DR: In this paper, the association between BV and BV-associated bacteria and expression of HIV in the female genital tract was examined by quantifying the polymerase chain reaction (PCR) in cervicovaginal lavage (CVL) samples.
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Utility of Amsel criteria, Nugent score, and quantitative PCR for Gardnerella vaginalis, Mycoplasma hominis, and Lactobacillus spp. for diagnosis of bacterial vaginosis in human immunodeficiency virus-infected women.
Beverly E. Sha,Hua Yun Chen,Qiong J. Wang,M. Reza Zariffard,Mardge H. Cohen,Gregory T. Spear +5 more
TL;DR: PCR quantification of G. vaginalis and M. hominis from CVL is significantly more sensitive than Amsel criteria for diagnosing BV, and Utilizing all three log10 bacterial counts in the model improved the sensitivity and specificity to 83% and 78%, respectively, in comparison with Nugent score.
Journal ArticleDOI
Proportional hazards regression with missing covariates
TL;DR: In this article, a nonparametric maximum likelihood (NPML) estimator is used to estimate regression parameters in a proportional hazards regression model with missing covariates, and EM type algorithms are applied to solve the maximization problem.
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A test of missing completely at random for generalised estimating equations with missing data
TL;DR: In this paper, a test for missing completely at random is proposed to help decide whether or not we should adjust estimating equations to correct the possible bias introduced by a missing-data mechanism that is not missing at random.
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Cervicovaginal Levels of Lactoferrin, Secretory Leukocyte Protease Inhibitor, and RANTES and the Effects of Coexisting Vaginoses in Human Immunodeficiency Virus (HIV)-Seronegative Women with a High Risk of Heterosexual Acquisition of HIV Infection
Richard M. Novak,Betty A. Donoval,Parrie Graham,Lucy A. Boksa,Gregory T. Spear,Ronald C. Hershow,Hua Yun Chen,Alan L. Landay +7 more
TL;DR: The higher Lf concentrations observed in high-risk women were strongly associated with the presence of leukocytes, suggesting a leukocyte source and consistent with greater genital tract inflammation in the high- Risk group, and the increased RANTES levels in a higher-risk subset of high- risk women were reduced after BV treatment.