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Showing papers by "Hui Zhang published in 2017"

Journal Article•DOI•
The E3 ubiquitin ligase SCFFBXL14 complex stimulates neuronal differentiation by targeting the Notch signaling factor HES1 for proteolysis

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Fangfang Chen1, Chunxiao Zhang1, Hao-Nan Wu1, Yue Ma1, Xiaomin Luo1, Xinqi Gong2, Fan Jiang1, Yaoting Gui1, Hui Zhang3, Fei Lu1 •
Peking University1, Renmin University of China2, University of Nevada, Las Vegas3
08 Dec 2017-Journal of Biological Chemistry
TL;DR: The results suggest that SCFFBXL14 promotes neuronal differentiation by targeting HES1 for ubiquitin-dependent proteolysis and that the C-terminal WRPW motif in H ES1 is required for this process.

14 citations