H
Hung Li
Researcher at Academia Sinica
Publications - 14
Citations - 1275
Hung Li is an academic researcher from Academia Sinica. The author has contributed to research in topics: Stem cell & Stroke. The author has an hindex of 13, co-authored 14 publications receiving 1233 citations. Previous affiliations of Hung Li include National Yang-Ming University.
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Journal ArticleDOI
Functional Recovery of Stroke Rats Induced by Granulocyte Colony-Stimulating Factor–Stimulated Stem Cells
Woei Cherng Shyu,Shinn Zong Lin,Hui I. Yang,Yi Shiuan Tzeng,Cheng-Yoong Pang,Pao Sheng Yen,Hung Li,Hung Li +7 more
TL;DR: Subcutaneous administration of G-CSF enhanced the availability of circulating hematopoietic stem cells to the brain and their capacity for neurogenesis and angiogenesis in rats with cerebral ischemia, reducing the volume of cerebral infarction and improving neural plasticity and vascularization.
Journal ArticleDOI
Granulocyte colony-stimulating factor for acute ischemic stroke: A randomized controlled trial
TL;DR: The preliminary evidence suggests that using G-CSF as therapy for acute stroke is safe and feasible and leads to improved neurologic outcomes.
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Intracerebral Peripheral Blood Stem Cell (CD34+) Implantation Induces Neuroplasticity by Enhancing β1 Integrin-Mediated Angiogenesis in Chronic Stroke Rats
TL;DR: In this study, rats receiving intracerebral peripheral blood hematopoietic stem cell (CD34+) (PBSC) transplantation showed much more improvement in neurological function after chronic cerebral ischemia in comparison with vehicle-treated control rats.
Journal ArticleDOI
Overexpression of PrPC by Adenovirus-Mediated Gene Targeting Reduces Ischemic Injury in a Stroke Rat Model
Woei Cherng Shyu,Shinn Zong Lin,Ming Fu Chiang,Dah-Ching Ding,Kuo Wei Li,Shih Fen Chen,Hui I. Yang,Hung Li,Hung Li +8 more
TL;DR: It is suggested that HSTF-1 (hypoxia-activated transcription factor), phosphorylated by ERK1/2, may in turn interact with HSE in the promoter of PrPC resulting in gene expression of the prion gene.
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Regenerative therapy for stroke.
TL;DR: Investigation of the molecular pathways involved in stem cell homing into the ischemic areas could pave the way for the development of new treatment regimens, perhaps using small molecules, designed to enhance endogeneous mobilization of stem cells in various disease states.