Spin trapping: ESR parameters of spin adducts.

An apparatus for cleansing wounds in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are recirculated by a device for moving fluid through a flow path which passes through the dressing and a means for fluid cleansing and back to the dressing. The cleansing means (which may be a single-phase, e.g. microfiltration, system or a two-phase, e.g. dialytic system) removes materials deleterious to wound healing, and the cleansed fluid, still containing materials that are beneficial in promoting wound healing, is returned to the wound bed. The dressing and a method of treatment using the apparatus.

Apparatus for aspirating, irrigating and cleansing wounds

Free-Radical Rearrangements

Anilines and ethyl vinyl ether can be used as precursors for a process that is the synthetic equivalent of the α-arylation of acetaldehyde enolate. The reaction manifests a high level of functional group compatibility, allowing the ready preparation of a number of synthetically valuable compounds.

Continuous-flow synthesis of monoarylated acetaldehydes using aryldiazonium salts.

A transition-metal-free synthesis of arylcarboxyamides from aryl diazonium salts and isocyanides.

Recent studies on novel reactions of thioamides, thioureas, and related compounds with various radical-forming agents such as phenylazotriphenylmethane, N-nitrosoacetanilides, and aryldiazonium salts are reviewed. The aryl radicals are shown to add to the sulphur atom of the fragments NH—CS—R or NH—CS—NH forming the adduct radicals NH—Ċ(SAr)—R and NH—Ċ (SAr)—NH, respectively. This is proven by isolation of the reaction products and by ESR spectroscopy. The main pathways of the adduct-radicals' transformations are the following: (i) Cross-disproportionation with other radicals due to hydrogen abstraction from an NH group yielding the S-aryl derivatives of isothioamides and isothioureas. (ii) Cross-disproportionation due to hydrogen abstraction from an α-CH group affording ketene N,S-acetals. (iii) “Growth” with the formation of bis-formamidine sulfides and bis-imidosulfides. (iv) Oxidation by CuII to isothiouronium salts. Some relations which permit to predict the reaction pathway depending on the...

Radical Reactions of Thioamides, Thioureas, and Related Compounds

The general aspects of the method for the identification and study of short-lived radicals in the liquid phase by EPR using spin-trapping agents are discussed and the available literature data for the application of the spin-trapping method to the study of short-lived chlorine- and sulphur-containing radicals and reactions involving them are surveyed. Certain methodological solutions, which make it possible to use the method in the study of complex radical reactions, are examined. The bibliography includes 91 references.

I. I. Kandror

Papers

Radical Reactions of Thioamides, Thioureas, and Related Compounds

Study of Short-lived Chlorine- and Sulphur-containing Radicals by the Spin-trapping Method

Eine neue radikalische reaktion in der reihe schwefelorganischer verbindungen. Phenylierung von thioharnstoff mit phenylazotriphenylmethan

Esr-untersuchung von radikalumlagerungen mit der “spin-trapping”-methode

ESR-untersuchung der homolytischen zersetzung von sulphonylhalogeniden