Thermospray negative ion mass spectra of eighteen steroid monoglucuronide conjugates have been recorded. The salt-free aqueous solvent system used gave mass spectra for glucuronides which contained molecular anions only. Selected ion monitoring indicated that as little as 100 pg of these compounds could be detected. A gradient elution high-performance liquid chromatography system has been developed and applied to separation of the individual components of a mixture of twelve steroid monoglucuronides and detection by thermospray liquid chromatography negative ion mass spectrometry.

Steroid glucronide conjugates: Analysis by thermospray liquid chromatography negative ion mass spectrometry

Effect of experimental conditions on the daughter ion spectra derived from tandem mass spectrometry of steroid glucuronides.

Quantification of steroid conjugates using fast atom bombardment mass spectrometry.

Use of positive ion fast atom bombardment mass spectrometry for rapid identification of a bile alcohol glucuronide isolated from cerebrotendinous xanthomatosis patients.

I. Jardine

Papers

Synthesis of mono- and diglucosiduronates of metabolites of deoxycorticosterone and corticosterone and analysis by a new mass spectrometric technique