There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality.

Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

I and i

Recent advance in research on halloysite nanotubes-polymer nanocomposite

Properties and applications of halloysite nanotubes: recent research advances and future prospects

A review on chitosan and its nanocomposites in drug delivery.

Internal hemorrhaging is a leading cause of death after traumatic injury on the battlefield. Although several surgical approaches such as the use of fibrin glue and tissue adhesive have been commercialized to achieve hemostasis, these approaches are difficult to employ on the battlefield and cannot be used for incompressible wounds. Here, we present shear-thinning nanocomposite hydrogels composed of synthetic silicate nanoplatelets and gelatin as injectable hemostatic agents. These materials are demonstrated to decrease in vitro blood clotting times by 77%, and to form stable clot-gel systems. In vivo tests indicated that the nanocomposites are biocompatible and capable of promoting hemostasis in an otherwise lethal liver laceration. The combination of injectability, rapid mechanical recovery, physiological stability, and the ability to promote coagulation result in a hemostat for treating incompressible wounds in out-of-hospital, emergency conditions.

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I. Salcedo

Papers

Current challenges in clay minerals for drug delivery

In vitro biocompatibility and mucoadhesion of montmorillonite chitosan nanocomposite: A new drug delivery

Release kinetics of 5-aminosalicylic acid from halloysite.

Chitosan-silicate biocomposites to be used in modified drug release of 5-aminosalicylic acid (5-ASA)

Folk pharmaceutical formulations in western Mediterranean: identification and safety of clays used in pelotherapy.