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I. Striz
Researcher at Charles University in Prague
Publications - 46
Citations - 1107
I. Striz is an academic researcher from Charles University in Prague. The author has contributed to research in topics: Transplantation & Kidney transplantation. The author has an hindex of 20, co-authored 39 publications receiving 987 citations.
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Cytokine networking of innate immunity cells: a potential target of therapy.
TL;DR: The innate immune system down-regulates effector mechanisms and restores homoeostasis in injured tissue via cytokines from the IL-10 and TGF (transforming growth factor) families mainly released from macrophages, preferentially the M2 subset, which have a capacity to induce regulatory T-cells.
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B-cell-related biomarkers of tolerance are up-regulated in rejection-free kidney transplant recipients.
Ondrej Viklicky,E. Krystufkova,Irena Brabcova,Alena Sekerkova,Peter Wohlfahrt,Petra Hribova,Mariana Wohlfahrtova,Birgit Sawitzki,Janka Slatinska,I. Striz,Hans-Dieter Volk,Petra Reinke +11 more
TL;DR: A significantly higher number of peripheral B cells were observed during follow-up in rejection-free patients and in patients with borderline changes, suggesting an association of B-cell signatures, seen also in drug-free tolerant patients, with controlled alloimmune response.
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Interleukin 18 (IL-18) upregulation in acute rejection of kidney allograft.
I. Striz,Eliska Krasna,Eva Honsova,Lácha J,Katerina Petrickova,Marcela Jaresova,A. Lodererova,Radka Bohmova,Sarka Valhova,Antonij Slavcev,Stefan Vitko +10 more
TL;DR: The upregulation of epithelial IL-18 plays an important role in immune and immunopathological reactions in renal parenchyma and contributes to rejection mechanisms of kidney allograft as discussed by the authors.
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Bronchoalveolar lavage fluid cellular characteristics, functional parameters and cytokine and chemokine levels in interstitial lung diseases.
Martina Vasakova,Martina Sterclova,L. Kolesar,Antonij Slavcev,Petr Pohunek,Jan Sulc,Jelena Skibova,I. Striz +7 more
TL;DR: BALF VEGF, IL‐8 and ENA‐78 levels and IL-8/ENA‐78 ratio could become useful markers of ILDs’ phase, activity and prognosis and might also be helpful in treatment modality choice.
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Regulatory T cells in kidney transplant recipients: the effect of induction immunosuppression therapy
TL;DR: In this study, the rATG induction therapy was associated with an expansion of regulatory cells and sustained high CD4(+)FoxP3(+)/Teff ratios were associated with the absence of rejection after basiliximab induction.