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Ian Y. Chen
Researcher at Stanford University
Publications - 75
Citations - 3557
Ian Y. Chen is an academic researcher from Stanford University. The author has contributed to research in topics: Reporter gene & Transplantation. The author has an hindex of 33, co-authored 67 publications receiving 3351 citations. Previous affiliations of Ian Y. Chen include Oklahoma State University Center for Health Sciences & Cardiovascular Institute of the South.
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Journal ArticleDOI
US imaging of tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice.
Juergen K. Willmann,Ramasamy Paulmurugan,Kai Chen,Olivier Gheysens,Martin Rodriguez-Porcel,Amelie M. Lutz,Ian Y. Chen,Xiaoyuan Chen,Sanjiv S. Gambhir +8 more
TL;DR: In this paper, a contrast agent consisting of encapsulated gaseous microbubbles was developed specifically to bind to vascular endothelial growth factor receptor type 2 (VEGFR2) for imaging tumor angiogenesis in two murine tumor models.
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Molecular Imaging of Cardiac Cell Transplantation in Living Animals Using Optical Bioluminescence and Positron Emission Tomography
Joseph C. Wu,Ian Y. Chen,Gobalakrishnan Sundaresan,Jung-Joon Min,Abhijit De,Jian-Hua Qiao,Michael C. Fishbein,Sanjiv S. Gambhir +7 more
TL;DR: The location(s), magnitude, and survival duration of embryonic cardiomyoblasts were monitored noninvasively and the in vivo images of cell survival were confirmed by ex vivo autoradiography, histology, immunohistochemistry, and reporter protein assays.
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Collagen Matrices Enhance Survival of Transplanted Cardiomyoblasts and Contribute to Functional Improvement of Ischemic Rat Hearts
Ingo Kutschka,Ian Y. Chen,Theo Kofidis,Takayasu Arai,Georges von Degenfeld,Ahmad Y. Sheikh,Stephen L. Hendry,Jeremy I. Pearl,Grant Hoyt,Ramachadra Sista,Phillip C. Yang,Helen M. Blau,Sanjiv S. Gambhir,Robert C. Robbins +13 more
TL;DR: Collagen matrices enhance early survival of H9c2 cardiomyoblasts after transplantation into ischemic hearts and lead to improved LV function.
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Induced pluripotent stem cells: at the heart of cardiovascular precision medicine
TL;DR: This Review summarizes the progress that has been made in the field of hiPSC technology, with particular emphasis on cardiovascular disease modelling and drug development, and the growing roles of hi PSC technology in the practice of precision medicine.
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Cardiovascular molecular imaging: focus on clinical translation.
Ian Y. Chen,Joseph C. Wu +1 more
TL;DR: The past few decades have seen an explosion in the knowledge of the molecular basis of cardiovascular diseases owing to rapid advances in molecular biology research, and molecular imaging techniques have been designed and validated to study much smaller-scale molecular events that may underlie disease processes.