Showing papers by "Indrapal Singh Aidhen published in 2009"
TL;DR: The Weinreb amide has proven to be an excellent acylating agent for organolithium or organomagnesium reagents and as a robust equivalent for an aldehyde group.
Abstract: SYNTHESIS 2008, No. 23, pp 3707–3738xx.xx.2008 Advanced online publication: 14.11.2008 DOI: 10.1055/s-0028-1083226; Art ID: E22008SS © Georg Thieme Verlag Stuttgart · New York Abstract: N-Methoxy-N-methylamide, popularly addressed as the Weinreb amide, has surfaced as an amide with a difference. This amide has served as an excellent acylating agent for organolithium or organomagnesium reagents and as a robust equivalent for an aldehyde group. These two aspects have been exploited exhaustively in various synthetic endeavors. This review presents the growing synthetic utility of the Weinreb amide not only in academic circles, but also its popular use on kilogram scale by various pharmaceutical industries across the globe.
22 citations
TL;DR: In this article, a distyrylbenzene derivative with end substituent as Weinreb amide was synthesized and the photophysical parameters of the dye were given.
7 citations
TL;DR: In this paper, a new and convenient synthesis of 2-O-benzyl-3, 4: 5, 6-di-Oisopropylidene-D-glucitol has been accomplished and has been generalized with the syntheses of differently protected Dglucitols at C-2 position.
5 citations
TL;DR: Two carbon chain homolgation of enantiopure four carbon erythro configured iodo derivative 5 with N-methoxy-N-methyl-2-phenylsulfonylacetamide 6 affords for the first time a stable and storable precursor 3 of D-amicetose in the acyclic form, wherein the sensitive aldehyde is masked as a Wcinreb amide as mentioned in this paper.
Abstract: Two carbon chain homolgation of enantiopure four carbon erythro configured iodo derivative 5 with N-methoxy-N-methyl-2-phenylsulfonylacetamide 6 affords for the first time a stable and storable precursor 3 of D-amicetose in the acyclic form, wherein the sensitive aldehyde is masked as a Wcinreb amide. The differential protection in this acyclic derivative offers all the potential to exclusively arrive at the pyranose form of the target dideoxy-sugar.
1 citations