I
Inez Ruiz-White
Publications - 9
Citations - 220
Inez Ruiz-White is an academic researcher. The author has contributed to research in topics: Aminosteroid & Diet-induced obese. The author has an hindex of 4, co-authored 8 publications receiving 193 citations.
Papers
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Journal ArticleDOI
Inhibition of PTP1B by trodusquemine (MSI-1436) causes fat-specific weight loss in diet-induced obese mice.
Kristen A. Lantz,Susan G. Emeigh Hart,Sonia Lobo Planey,Mitchell F. Roitman,Inez Ruiz-White,Henry R. Wolfe,Michael Mclane +6 more
TL;DR: The data establish trodusquemine as an effective central and peripheral PTP1B inhibitor with the potential to elicit noncachectic fat‐specific weight loss and improve insulin and leptin levels.
Patent
A method for treating diabetes
TL;DR: In this paper, the use of steroid compounds for the selective inhibition of the enzyme PTP1B in a mammal for the treatment of diabetes was proposed, which was shown to be effective.
Patent
Aminosteroids for the treatment of a ptp1b associated disease
TL;DR: In this paper, the use of aminosteroid compounds for the selective inhibition of the enzyme PTP1B in a mammal for the treatment of diabetes was proposed, which was shown to be effective.
Patent
Method for treating diabetes
TL;DR: In this paper, the use of steroid compounds for the selective inhibition of the enzyme PTP1B in a mammal for the treatment of diabetes was proposed, which was shown to be effective.
Patent
A method for treating rapamycin induced diabetes-like syndrome using trodusquemine
Abstract: This invention relates to the use of trodusquemine to treat a rapamycin-induced diabetic- like syndrome in a mammal. Data is presented demonstrating that trodusquemine can reverse short term and long term glucose intolerance and can reverse hyperglycemia in a diet induced obese animal.