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Ioan Jung

Researcher at University of Medicine, Pharmacy, Science and Technology of Târgu Mureș

Publications -  135
Citations -  1522

Ioan Jung is an academic researcher from University of Medicine, Pharmacy, Science and Technology of Târgu Mureș. The author has contributed to research in topics: Maspin & Cancer. The author has an hindex of 18, co-authored 124 publications receiving 1167 citations. Previous affiliations of Ioan Jung include Hai phong University Of Medicine and Pharmacy & Yahoo!.

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Systematic review of the old and new concepts in the epithelial-mesenchymal transition of colorectal cancer.

TL;DR: The main conclusion is that, although many studies have been published, the EMT features are still incompletely elucidated and newly discovered EMT markers provide confusing data in understanding this complicated process, which might have significant clinical impact.
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Epithelial-mesenchymal, mesenchymal-epithelial, and endothelial-mesenchymal transitions in malignant tumors: An update.

TL;DR: The authors tried to present the latest data about the particularities of these processes, and also of the so-called endothelial-to-mesenchymal transition, based on tumor location, as well as a possible valuable parameter for clinical follow-up and targeted therapeutic oncologic management.
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Epithelial Mesenchymal and Endothelial Mesenchymal Transitions in Hepatocellular Carcinoma: A Review.

TL;DR: The metastatic pathway of HCC seems to be related to the Wnt- or, rather, TGFβ1-mediated inflammation-angiogenesis-EMT-CSCs crosstalk link, and molecular therapy should target this molecular axis controlling the HCC microenvironment.
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Mixed adenoneuroendocrine carcinoma of gastrointestinal tract: Report of two cases

TL;DR: Independently by the localization and tumor stage, MANECs appear to be highly malignant tumors, with high risk for distant metastases, and the aggressiveness seems to depend on the endocrine component, independent of its proportion.
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Aberrant pattern of the cytokeratin 7/cytokeratin 20 immunophenotype in colorectal adenocarcinomas with BRAF mutations

TL;DR: It seems that in case of MSI located on the proximal colon, which also presents BRAF mutations, CK20/CK7 may present a changing immunophenotype pattern, which may complicate the differential diagnosis of metastatic tumors.