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Showing papers by "Iradj Sobhani published in 2012"

Journal Article•DOI•
Randomized phase III trial in elderly patients comparing LV5FU2 with or without irinotecan for first-line treatment of metastatic colorectal cancer (FFCD 2001–02)

[...]

Thomas Aparicio1, Sandrine Lavau-Denes, Jean-Marc Phelip, Emilie Maillard, Jean-Louis Jouve, D. Gargot, Mohamed Gasmi, Christophe Locher, X. Adhoute, Pierre Michel, Faiza Khemissa, Thierry Lecomte, J. Provençal, Gilles Breysacher, Jean-Louis Legoux, Céline Lepère, J. Charneau, J. Cretin, L. Chone, A. Azzedine, O. Bouche, Iradj Sobhani, Laurent Bedenne, Emmanuel Mitry2, P. Amoyal, D. Auby, Jean-Baptiste Bachet, M. Baconnier, R. Benoit, O. Berthelet, Anne Thirot Bidault, C. Bineau, G. Bordes, Nadia Bouarioua, Eveline Boucher, O. Boulat, D. Cleau, P. Couzigou, E. Cuillerier, I. Cumin, B. Denis, F. Di Fiore, V. Derias, J. Ezenfis, Roger Faroux, A. Gagnaire, G. Gatineau-Sailliant, B. Garcia, Dominique Genet, A. Gueye, Pascal Hammel, J.P. Lagasse, B. Landi, Côme Lepage, C. Lobry, Catherine Lombard-Bohas, May Mabro, R. Mackiewicz, J. Martin, X. Moncoucy, François Morvan, M. Mozer, M. Pauwels, F. Petit-Laurent, P. Pouderoux, P. Prost, A.M. Queuniet, Mohamed Ramdani, C. Rebischung, Ph. Rougier, Matthieu Schnee, Jean-François Seitz, L. Stefani, Julien Taieb, Eric Terrebonne, Patrick Texereau, J. Thaury, David Tougeron, Achim Weber, F. Ricard, F. Bonnetain, F. Masskouri, C. Choine, F. Guiliani, G. Le Pessec, H. Fattouh, N. Le Provost, C. Girault, M. Schneider •
Sorbonne1, Curie Institute2
01 Sep 2012-Annals of Oncology
TL;DR: In this elderly population, adding irinotecan to an infusional 5-FU-based CT did not significantly increase either PFS or OS, and Classic LV5FU2 was associated with an improved OS compared with simplified LV 5FU2.

79 citations

Journal Article•DOI•
Design of a specific colonic mucus marker using a human commensal bacterium cell surface domain.

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Yves-Marie Coïc, Françoise Baleux1, Oemer Poyraz2, Roman Thibeaux, Elisabeth Labruyère, Fabrice Chrétien, Iradj Sobhani, Thierry Lazure, Benjamin Wyplosz, Gunter Schneider2, Laurence A Mulard1, Philippe J. Sansonetti3, Philippe J. Sansonetti4, Benoit S. Marteyn3 •
Centre national de la recherche scientifique1, Karolinska Institutet2, Pasteur Institute3, Collège de France4
04 May 2012-Journal of Biological Chemistry
TL;DR: Cy5-MUB70 is a novel and specific fluorescent marker for mammalian colonic mucus that may be used for live imaging analysis but also as a marker for the diagnosis and the prognosis of Colonic mucinous carcinomas.

26 citations