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Irene Andia Biraro
Researcher at College of Health Sciences, Bahrain
Publications - 19
Citations - 206
Irene Andia Biraro is an academic researcher from College of Health Sciences, Bahrain. The author has contributed to research in topics: Latent tuberculosis & Tuberculosis. The author has an hindex of 7, co-authored 19 publications receiving 141 citations. Previous affiliations of Irene Andia Biraro include Uganda Virus Research Institute & Makerere University.
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Journal ArticleDOI
The Use of Interferon Gamma Inducible Protein 10 as a Potential Biomarker in the Diagnosis of Latent Tuberculosis Infection in Uganda.
Irene Andia Biraro,Irene Andia Biraro,Simon G. Kimuda,Simon G. Kimuda,Moses Egesa,Moses Egesa,Stephen Cose,Stephen Cose,Emily L. Webb,Moses Joloba,Steven G. Smith,Alison M. Elliott,Alison M. Elliott,Hazel M. Dockrell,Achilles Katamba +14 more
TL;DR: IP-10 performed well in differentiating contacts with either latent or active TB from those who were uninfected but was not able to differentiate LTBI from active disease except when MTB specific to mitogen specific ratios were used in HIV negative adults.
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Effect of isoniazid preventive therapy on immune responses to mycobacterium tuberculosis: an open label randomised, controlled, exploratory study
Irene Andia Biraro,Moses Egesa,Simon G. Kimuda,Steven G. Smith,Frederic Toulza,Jonathan Levin,Jonathan Levin,Moses Joloba,Achilles Katamba,Stephen Cose,Stephen Cose,Hazel M. Dockrell,Alison M. Elliott,Alison M. Elliott +13 more
TL;DR: IPT led to a decrease in Th1 cytokine production, and also in the anti CFP-10 antibody concentration, and this could be secondary to a reduction in mycobacterial burden or as a possible direct effect of isoniazid induced T cell apoptosis.
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Impact of Co-Infections and BCG Immunisation on Immune Responses among Household Contacts of Tuberculosis Patients in a Ugandan Cohort
Irene Andia Biraro,Moses Egesa,Frederic Toulza,Jonathan Levin,Stephen Cose,Moses Joloba,Steven G. Smith,Hazel M. Dockrell,Achilles Katamba,Alison M. Elliott +9 more
TL;DR: No evidence that co-infections increase the risk of LTBI, or influence the cytokine response profile among those with LTBI is found; prior BCG exposure may reduce Th1 cytokine responses in LTBI.
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Circulating B-lymphocytes as potential biomarkers of tuberculosis infection activity.
TL;DR: It is demonstrated that peripheral blood B-cell responses are differentially modulated during latent and active M. tuberculosis infection, and suggested that the PB to MBC ratio may be a useful biomarker of TB infection activity.
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The 'Indirect Costs' of Underfunding Foreign Partners in Global Health Research: A Case Study
TL;DR: It is argued that U.S. fiscal administrative practices may drain rather than build capacity at African universities by underfunding the administrative costs of global health research, circumventing host country institutions, and externalising legal and financial risks associated with international work.