Showing papers by "Irwin M. Arias published in 1990"

PDF

Open Access

Journal Article•DOI•

Mechanism of the lack of induction of UDP-glucuronosyltransferase activity in Gunn rats by 3-methylcholanthrene. Identification of a truncated enzyme.

[...]

Mostafa K. El-Awady¹, Jayanta Roy Chowdhury¹, K. Kesari¹, H. H.G. Van Es¹, P. L. M. Jansen¹, M. Lederstein¹, Irwin M. Arias¹, Namita Roy Chowdhury¹ - Show less +4 more•Institutions (1)

Albert Einstein College of Medicine¹

25 Jun 1990-Journal of Biological Chemistry

TL;DR: Results suggest that a sequence abnormality in the 3-MC-inducible UDPGT mRNA in Gunn rats results in reduced mRNA concentration and synthesis of a truncated, enzymically inactive UDPGT.

...read moreread less

39 citations