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Iván Gallegos
Researcher at University of Chile
Publications - 30
Citations - 471
Iván Gallegos is an academic researcher from University of Chile. The author has contributed to research in topics: Cancer & Metastasis. The author has an hindex of 10, co-authored 27 publications receiving 347 citations.
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Proapoptotic effect of endocannabinoids in prostate cancer cells.
Octavio Orellana-Serradell,Cristian Poblete,Catherine Sánchez,Enrique A. Castellón,Iván Gallegos,C. A. Huidobro,Miguel N. Llanos,Héctor R. Contreras +7 more
TL;DR: It is suggested that endocannabinoids may be a beneficial option for the treatment of prostate cancer that has become nonresponsive to common therapies.
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The expression of syndecan-1 and -2 is associated with Gleason score and epithelial-mesenchymal transition markers, E-cadherin and β-catenin, in prostate cancer
Héctor R. Contreras,Rodrigo Ledezma,Jorge Vergara,Federico Cifuentes,Cristina Barra,Pablo Cabello,Iván Gallegos,Bernardo Morales,Christian Huidobro,Enrique A. Castellón +9 more
TL;DR: Changes in expression and cell distribution of E-cadherin and beta-catenin correlated with the progression degree of prostate adenocarcinoma, suggesting a role of these molecules as markers of progression and prognosis.
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Molecular signature of cancer stem cells isolated from prostate carcinoma and expression of stem markers in different Gleason grades and metastasis.
Enrique A. Castellón,Rodrigo Valenzuela,Jorge Lillo,Viviana Castillo,Héctor R. Contreras,Iván Gallegos,Alejandro Mercado,Christian Huidobro +7 more
TL;DR: It is suggested that the CSCs in PCa reach an important number in medium Gleason grades, when the tumor is still confined into the gland, and may be a prognosis factor for PCa recurrence.
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Increased SNAIL expression and low syndecan levels are associated with high Gleason grade in prostate cancer
Cristian Poblete,Juan Fulla,Marcela Gallardo,Valentina Muñoz,Enrique A. Castellón,Iván Gallegos,Héctor R. Contreras +6 more
TL;DR: Analyzing immunochemically the expression of SNAIL, syndecans 1 and 2 and other EMT markers in a tissue microarray of PC samples and PC cell lines concluded that increased SNAil levels in advanced PC are associated with low expression of syndecan 1.
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Tumor lysate-based vaccines: on the road to immunotherapy for gallbladder cancer
Daniel Rojas-Sepúlveda,Andrés Tittarelli,María Alejandra Gleisner,Ignacio Ávalos,Cristián Pereda,Iván Gallegos,Fermín E. González,Mercedes N. López,Jean Michel Butte,Juan Carlos Roa,Paula Fluxá,Flavio Salazar-Onfray +11 more
TL;DR: Evaluated the feasibility of producing effective dendritic cell (DC) based vaccines using heat-conditioned cell lysates derived from gallbladder cancer cell lines (GBCCL) and found that they expressed some tumor-associated antigens such as CEA, MUC-1, CA19-9, Erb2, Survivin, and several carcinoembryonicAntigens.