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Showing papers by "Ivo José Curcino Vieira published in 2012"


Journal ArticleDOI
TL;DR: The inhibitory effects of the ethyl acetate extract and capsaicin and dihydrocapsaicin isolated from fruits of Capsicum annuum chili pepper type, and synthetic capsicinoid derivatives at different concentrations were evaluated against Streptococcus mutans.
Abstract: The inhibitory effects of the ethyl acetate extract and capsaicin (1) and dihydrocapsaicin (2) isolated from fruits of Capsicum annuum chili pepper type, and synthetic capsaicinoid derivatives (N-(4-hydroxyphenylethyl)decamide (3), (E)-N-(4-hydroxy-3-methoxybenzyl)-3,7-dimethylocta-2,6-dienamide (4), 4-hydroxy-3-methoxy-N-((E)-3,7-dimethylocta-2,6-dienyl)benzamide (5) and N-(4-hydroxy-3-methoxybenzyl)decamide (6) at different concentrations were evaluated against Streptococcus mutans. The minimum inhibitory concentration at which the ethyl acetate extract prevented the growth of S. mutans was 2.5 mg/mL; those of the isolated compounds 1 and 2 were 1.25 μg/mL, while 3 was 5.0 μg/mL, and 4, 5 and 6 were 2.5 μg/mL, respectively.

34 citations


Journal ArticleDOI
TL;DR: In this paper, a triterpene, 1-epi castanopsol, was isolated from the wood of Simira glaziovii, and detailed spectral data analyses allowed the definition of the structure of the new 1epi isomer of castanopol and performance of 1H and 13C NMR chemical shift assignments.
Abstract: A new triterpene, 1-epi-castanopsol, besides eleven known compounds: sitosterol, stigmasterol, campesterol, lupeol, lupenone, simirane B, syringaresinol, scopoletin, isofraxidin, 6,7,8-trimethoxycoumarin and harman, were isolated from the wood of Simira glaziovii. The structures of the known compounds were defined by 1D, 2D 1H, 13C NMR spectra data analyses and comparison with literature data. The detailed spectral data analyses allowed the definition of the structure of the new 1-epi isomer of castanopsol and performance of 1H and 13C NMR chemical shift assignments.

8 citations